Results 21 to 30 of about 3,226 (181)

American rattlesnake (Crotalus durissus terrificus) bite accidents in dogs in Argentina

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2000
The symptomatology and treatment of two dogs bitten by Crotalus durissus terrificus are described. Neurological signs were present few minutes after the accident with local anesthesia and ataxia of the affected limb and neurotoxic fascia.
P. Koscinczuk, O. Acosta de Pérez, P. Teibler, S. Maruñak, A.S. Rosciani   +4 more
doaj   +2 more sources

Crotoxin Isolated from Crotalus durissus terrificus Venom Modulates the Functional Activity of Dendritic Cells via Formyl Peptide Receptors. [PDF]

J Immunol Res, 2018
The Crotalus durissus terrificus rattlesnake venom, its main toxin, crotoxin (CTX), and its crotapotin (CA) and phospholipase A2 (CB) subunits modulate the immune system. Formyl peptide receptors (FPRs) and lipoxin A4 (LXA4) are involved in CTX’s effect on macrophages and neutrophils. Dendritic cells (DCs) are plasticity cells involved in the induction
Freitas AP, Favoretto BC, Clissa PB, Sampaio SC, Faquim-Mauro EL.   +4 more
europepmc   +2 more sources

In vivo and in vitro prospection of the anti-ophidic properties exercised by the extracts of Jacaranda decurrens L.

Acta Scientiarum: Biological Sciences, 2021
The research and development of alternative treatments for snakebites (e.g., medicinal plants) is necessary due to the high costs of the existing ones.
Marcus Vinícius Cardoso Trento, Mateus Santos Carapiá, Pedro Henrique Souza César, Mariana Aparecida Braga, Andreimar Martins Soares, Silvana Marcussi   +5 more
doaj   +1 more source

Afibrinogenemia Following Snake Bite (Crotalus Durissus Terrificus) [PDF]

The American Journal of Tropical Medicine and Hygiene, 1980
Following the bite of Crotalus durissus terrificus, an 11-year-old boy developed afibrinogenemia and high output acute renal failure. His platelet count remained within normal limits. He was treated with epsilon aminocaproic acid and whole fresh blood transfusion, with full recovery from afibrinogenemia 40 hours after the beginning of these measures ...
C F, Amaral, O A, da Silva, M, López, E R, Pedroso   +3 more
openaire   +2 more sources

Peptidase activities in Crotalus durissus terrificus semen [PDF]

REPRODUCTION, 2008
AbstractTo understand the role of peptidases in seminal physiology of Crotalus durissus terrificus, activity levels of representative enzymes in semen and their sensitivities to inhibitors, cofactors, and peptide hormones were evaluated. The existence of seminal fractions and the association of peptidases with these fractions were also characterized ...
Camila Eduardo, Marinho, Selma Maria, Almeida-Santos, Sylvia Mendes, Carneiro, Simone Cristina, Yamasaki, Paulo Flavio, Silveira   +4 more
openaire   +2 more sources

Cell Penetrating Peptides: Classification, Mechanisms, Methods of Study, and Applications

ChemMedChem, Volume 18, Issue 17, September 1, 2023., 2023
Cell penetrating peptides constitute a heterogeneous class of peptides with peculiar features that make them particularly well‐suited for the delivery of almost every type of molecule. Due to their versatility, they are becoming increasingly important in various biomedical applications.
Alessandro Gori, Giulia Lodigiani, Stella G. Colombarolli, Greta Bergamaschi, Alberto Vitali   +4 more
wiley   +1 more source

Anti‐Metalloprotease P‐I Single‐Domain Antibodies: Tools for Next‐Generation Snakebite Antivenoms

BioMed Research International, Volume 2022, Issue 1, 2022., 2022
In order to address the global antivenom crisis, novel antivenoms need to present high therapeutic efficacy, broad neutralization ability against systemic and local damage, sufficient safety, and cost‐effectiveness. Due to biological characteristics of camelid single‐domain antibodies (VHH) such as high affinity, their ability to penetrate dense ...
Marcela C. S. Silva, Soraya S. Pereira, Marilia P. Gouveia, Marcos B. Luiz, Rosa M. O. Sousa, Anderson M. Kayano, Aleff F. Francisco, Nidiane D. R. Prado, Leandro S. M. Dill, Marcos R. M. Fontes, Fernando B. Zanchi, Rodrigo G. Stabeli, Andreimar M. Soares, Juliana P. Zuliani, Carla F. C. Fernandes, Carla F. C. Fernandes   +15 more
wiley   +1 more source

New generation of cell‐penetrating peptides: Functionality and potential clinical application

Journal of Peptide Science, Volume 27, Issue 5, May 2021., 2021
New generation of CPPs achieves high uptake efficiency, cell‐ and tissue‐selective internalization, escape from endosomes, stability against proteases, and low toxicity against healthy cells. Certain members are derived from natural sources, and some of them exhibit innate tumor selectivity.
Siegmund Reissmann, Margarita P. Filatova   +1 more
wiley   +1 more source

Geographic variation of individual venom profile of Crotalus durissus snakes [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases, 2020
Background: South American rattlesnakes are represented in Brazil by a single species, Crotalus durissus, which has public health importance due to the severity of its envenomation and to its wide geographical distribution.
Leandro Norberto da Silva-Júnior, Lara de Souza Abreu, Caroline Fabri Bittencourt Rodrigues, Nathália da Costa Galizio, Weslei da Silva Aguiar, Caroline Serino-Silva, Valdomiro Souza dos Santos, Isabella Alves Costa, Luis Vicente Franco Oliveira, Sávio Stefanini Sant’Anna, Kathleen Fernandes Grego, Anita Mitico Tanaka-Azevedo, Leandro Nascimento da Silva Rodrigues, Karen de Morais-Zani   +13 more
doaj   +1 more source

Production, Transmission, Pathogenesis, and Control of Dengue Virus: A Literature‐Based Undivided Perspective

BioMed Research International, Volume 2021, Issue 1, 2021., 2021
Dengue remains one of the most serious and widespread mosquito‐borne viral infections in human beings, with serious health problems or even death. About 50 to 100 million people are newly infected annually, with almost 2.5 billion people living at risk and resulting in 20,000 deaths.
Muhammad Torequl Islam, Cristina Quispe, Jesús Herrera-Bravo, Chandan Sarkar, Rohit Sharma, Neha Garg, Larry Ibarra Fredes, Miquel Martorell, Mohammed M. Alshehri, Javad Sharifi-Rad, Sevgi Durna Daştan, Daniela Calina, Radi Alsafi, Saad Alghamdi, Gaber El-Saber Batiha, Natália Cruz-Martins, Cassiano Felippe Gonçalves-de-Albuquerque   +16 more
wiley   +1 more source