Results 31 to 40 of about 5,194 (183)

Geographic variation of individual venom profile of Crotalus durissus snakes [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases, 2020
Background: South American rattlesnakes are represented in Brazil by a single species, Crotalus durissus, which has public health importance due to the severity of its envenomation and to its wide geographical distribution.
Leandro Norberto da Silva-Júnior, Lara de Souza Abreu, Caroline Fabri Bittencourt Rodrigues, Nathália da Costa Galizio, Weslei da Silva Aguiar, Caroline Serino-Silva, Valdomiro Souza dos Santos, Isabella Alves Costa, Luis Vicente Franco Oliveira, Sávio Stefanini Sant’Anna, Kathleen Fernandes Grego, Anita Mitico Tanaka-Azevedo, Leandro Nascimento da Silva Rodrigues, Karen de Morais-Zani   +13 more
doaj   +1 more source

Anti‐Metalloprotease P‐I Single‐Domain Antibodies: Tools for Next‐Generation Snakebite Antivenoms

BioMed Research International, Volume 2022, Issue 1, 2022., 2022
In order to address the global antivenom crisis, novel antivenoms need to present high therapeutic efficacy, broad neutralization ability against systemic and local damage, sufficient safety, and cost‐effectiveness. Due to biological characteristics of camelid single‐domain antibodies (VHH) such as high affinity, their ability to penetrate dense ...
Marcela C. S. Silva, Soraya S. Pereira, Marilia P. Gouveia, Marcos B. Luiz, Rosa M. O. Sousa, Anderson M. Kayano, Aleff F. Francisco, Nidiane D. R. Prado, Leandro S. M. Dill, Marcos R. M. Fontes, Fernando B. Zanchi, Rodrigo G. Stabeli, Andreimar M. Soares, Juliana P. Zuliani, Carla F. C. Fernandes, Carla F. C. Fernandes   +15 more
wiley   +1 more source

New generation of cell‐penetrating peptides: Functionality and potential clinical application

Journal of Peptide Science, Volume 27, Issue 5, May 2021., 2021
New generation of CPPs achieves high uptake efficiency, cell‐ and tissue‐selective internalization, escape from endosomes, stability against proteases, and low toxicity against healthy cells. Certain members are derived from natural sources, and some of them exhibit innate tumor selectivity.
Siegmund Reissmann, Margarita P. Filatova   +1 more
wiley   +1 more source

Crotalus durissus terrificus venom as a source of antitumoral agents [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases, 2010
The basic knowledge on neoplasms is increasing quickly; however, few advances have been achieved in clinical therapy against tumors. For this reason, the development of alternative drugs is relevant in the attempt to improve prognosis and to increase patients' survival. Snake venoms are natural sources of bioactive substances with therapeutic potential.
Soares, MA, Pujatti, PB, Fortes-Dias, CL, Antonelli, L, Santos, RG   +4 more
openaire   +4 more sources

Production, Transmission, Pathogenesis, and Control of Dengue Virus: A Literature‐Based Undivided Perspective

BioMed Research International, Volume 2021, Issue 1, 2021., 2021
Dengue remains one of the most serious and widespread mosquito‐borne viral infections in human beings, with serious health problems or even death. About 50 to 100 million people are newly infected annually, with almost 2.5 billion people living at risk and resulting in 20,000 deaths.
Muhammad Torequl Islam, Cristina Quispe, Jesús Herrera-Bravo, Chandan Sarkar, Rohit Sharma, Neha Garg, Larry Ibarra Fredes, Miquel Martorell, Mohammed M. Alshehri, Javad Sharifi-Rad, Sevgi Durna Daştan, Daniela Calina, Radi Alsafi, Saad Alghamdi, Gaber El-Saber Batiha, Natália Cruz-Martins, Cassiano Felippe Gonçalves-de-Albuquerque   +16 more
wiley   +1 more source

Bilateral posterior circulation stroke secondary to a crotalid envenomation: case report

Revista da Sociedade Brasileira de Medicina Tropical, 2013
Snake bite envenoming is a disease with potential serious neurological complications. We report a case of an adolescent who was bitten by a rattlesnake and developed bilateral posterior circulation stroke.
Thiago Cardoso Vale, Alysson Ferreira Leite, Priscila Ribeiro da Hora, Marayra Inês França Coury, Ricardo Cipriano da Silva, Antônio Lúcio Teixeira   +5 more
doaj   +3 more sources

Transferência do Hepatozoon tupinambis, parasita do lagarto Tupinambis teguixin, para a serpente cascavel (Crotalus durissus terrificus), por intermédio do mosquito Culex fatigans

Memorias do Instituto Oswaldo Cruz, 1974
Os autores obtiveram a transferência do Hepatozoon tupinambis (Laveran e Salibeni, 1909) parasita do lagarto Teiidae, Tupinambis teguixin, L., para a serpente cascavel, Crotalus durissus terrificus (Laur.), alimentando-a com mosquitos experimentalmente ...
Samuel B. Pessôa, Persio de Biasi, Giuseppe Puorto   +2 more
doaj   +1 more source

Prevalence of Hepatozoon spp. (Apicomplexa, Hepatozoidae) among recently captured Brazilian snakes

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2003
The goal of this study was to determine the prevalence of Hepatozoon spp. infection in recently captured snakes from Botucatu, São Paulo State, Brazil. Blood was collected from all snakes by ventral tail venipuncture.
L.H. O'Dwyer, T.C. Moço, T.H. Barrella, F.C. Vilela, R.J. Silva   +4 more
doaj   +1 more source

Immunization with native and cobalt 60-irradiated Crotalus durissus terrificus venom in swiss mice: assessment of the neutralizing potency of antisera

Journal of Venomous Animals and Toxins including Tropical Diseases, 2005
ELISA was used to evaluate, follow, and compare the humoral immune response of Swiss mice during hyperimmunization with natural and Cobalt 60-irradiated (60Co) Crotalus durissus terrificus venom.
R. S. Ferreira Junior, N. Nascimento, J. C. Martinez, J. B. Alves, D. A. Meira, B. Barraviera   +5 more
doaj   +1 more source

Crotoxin-Induced Mice Lung Impairment: Role of Nicotinic Acetylcholine Receptors and COX-Derived Prostanoids

Biomolecules, 2020
Respiratory compromise in Crotalus durissus terrificus (C.d.t.) snakebite is an important pathological condition. Considering that crotoxin (CTX), a phospholipase A2 from C.d.t. venom, is the main component of the venom, the present work investigated the
Marco Aurelio Sartim, Camila O. S. Souza, Cassiano Ricardo A. F. Diniz, Vanessa M. B. da Fonseca, Lucas O. Sousa, Ana Paula F. Peti, Tassia Rafaella Costa, Alan G. Lourenço, Marcos C. Borges, Carlos A. Sorgi, Lucia Helena Faccioli, Suely Vilela Sampaio   +11 more
doaj   +1 more source