Results 21 to 30 of about 5,194 (183)

Crotalus durissus terrificus crotapotin naturally displays preferred positions for amino acid substitutions [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases, 2017
Background Classically, Crotalus durissus terrificus (Cdt) venom can be described, according to chromatographic criteria, as a simple venom, composed of four major toxins, namely: gyroxin, crotamine, crotoxin and convulxin.
Laudicéia Alves de Oliveira, Rui Seabra Ferreira, Benedito Barraviera, Francilene Capel Tavares de Carvalho, Luciana Curtolo de Barros, Lucilene Delazari dos Santos, Daniel Carvalho Pimenta   +6 more
doaj   +2 more sources

Role of crotoxin, a phospholipase A2 isolated from Crotalus durissus terrificus snake venom, on inflammatory and immune reactions [PDF]

Mediators of Inflammation, 2001
Background: Crotoxin (CTX) is a potent neurotoxin from Crotalus durissus terrificus snake venom (CdtV) composed of two subunits: one without catalytic activity (crotapotin), and a basic phospolipase A2.
Diva F. Cardoso, Monica Lopes-Ferreira, Eliana L. Faquim-Mauro, Mahasti S. Macedo, Sandra H. P. Farsky   +4 more
doaj   +2 more sources

Allopurinol reduces the lethality associated with acute renal failure induced by Crotalus durissus terrificus snake venom: comparison with probenecid. [PDF]

PLoS Neglected Tropical Diseases, 2011
BACKGROUND: Acute renal failure is one of the most serious complications of envenoming resulting from Crotalus durissus terrificus bites. This study evaluated the relevance of hyperuricemia and oxidative stress and the effects of allopurinol and ...
Rodrigo Frezzatti, Paulo Flavio Silveira
doaj   +2 more sources

Immunomodulatory properties of venom-derived crotamine [PDF]

Frontiers in Pharmacology
Crotamine is a low-molecular-weight cationic polypeptide isolated from Crotalus durissus terrificus snake venom, classified as a non-enzymatic toxin with distinctive structural and functional properties. This toxin also exhibits characteristics of a cell-
Isadora Oliveira, Isabela Ferreira, Lorena Sousa, João Alberghini-dos-Santos, Felipe Cerni, Manuela Pucca   +5 more
doaj   +2 more sources

Techniques of artificial insemination in Crotalus durissus terrificus (Viperidae-Crotalinae)

, 1994
Machos e fêmeas (n= 12) de Crotalus durissus terrificus, nascidos em cativeiro foram usados para testar a técnica de Inseminação Artificial. O esperma diluído foi introduzido na vagina e após 120 dias, 3 fêmeas foram dissecadas para exame. Outras 3 tiverarn a gestação levada a termo e produziram filhotes normais. Não foram observados ovos atrésicos.
Langlada, Francisco Garcia de, Santos, Selma, Ferreira, Iara Lucia Laporta   +2 more
openaire   +3 more sources

In vivo and in vitro prospection of the anti-ophidic properties exercised by the extracts of Jacaranda decurrens L.

Acta Scientiarum: Biological Sciences, 2021
The research and development of alternative treatments for snakebites (e.g., medicinal plants) is necessary due to the high costs of the existing ones.
Marcus Vinícius Cardoso Trento, Mateus Santos Carapiá, Pedro Henrique Souza César, Mariana Aparecida Braga, Andreimar Martins Soares, Silvana Marcussi   +5 more
doaj   +1 more source

Peptidase activities in Crotalus durissus terrificus semen [PDF]

Reproduction, 2008
Abstract To understand the role of peptidases in seminal physiology of Crotalus durissus terrificus, activity levels of representative enzymes in semen and their sensitivities to inhibitors, cofactors, and peptide hormones were evaluated.
Camila Eduardo, Marinho, Selma Maria, Almeida-Santos, Sylvia Mendes, Carneiro, Simone Cristina, Yamasaki, Paulo Flavio, Silveira   +4 more
openaire   +2 more sources

The origin of the diversity of crotoxin isoforms in the venom of Crotalus durissus terrificus [PDF]

European Journal of Biochemistry, 1994
Crotoxin, the main toxin from the venom of the South American rattlesnake Crotalus durissus terrificus, is a β‐neurotoxin which consists of the non‐covalent association of two subunits: a phospholipase A2 subunit B (CB), and a non‐enzymic subunit A (CA).
G, Faure, V, Choumet, C, Bouchier, L, Camoin, J L, Guillaume, B, Monegier, M, Vuilhorgne, C, Bon   +7 more
openaire   +2 more sources

Purification, crystallization and preliminary X-ray diffraction analysis of crotamine, a myotoxic polypeptide from the Brazilian snakeCrotalus durissus terrificus [PDF]

Acta Crystallographica Section F: Structural Biology Communications, 2012
Patrick Spencer, Christian Betzel, Monika A Coronado   +2 more
exaly   +2 more sources

Cell Penetrating Peptides: Classification, Mechanisms, Methods of Study, and Applications

ChemMedChem, Volume 18, Issue 17, September 1, 2023., 2023
Cell penetrating peptides constitute a heterogeneous class of peptides with peculiar features that make them particularly well‐suited for the delivery of almost every type of molecule. Due to their versatility, they are becoming increasingly important in various biomedical applications.
Alessandro Gori, Giulia Lodigiani, Stella G. Colombarolli, Greta Bergamaschi, Alberto Vitali   +4 more
wiley   +1 more source