Results 61 to 70 of about 3,226 (181)

Antivenom against Crotalus durissus terrificus venom: Immunochemical reactivity and experimental neutralizing capacity

Toxicon, 2017
The venom of Crotalus durissus terrificus produces a neurotoxic and myotoxic syndrome that can lead to the death. Specific antivenom is the only treatment to neutralize the toxicity of the venom and the precocity in applying the antivenom is crucial for the efficiency of the treatment.
Baudou, F. G., Litwin, S., Lanari, L. C., Laskowicz, R. D., Damin, C. F., /Chippaux, Jean-Philippe, de Roodt, A. R.   +6 more
openaire   +4 more sources

Animal Venoms as Peptide Libraries for the Discovery of Antiglioblastoma Agents

Biochemistry Research International, Volume 2026, Issue 1, 2026.
Glioblastoma is one of the most aggressive and widely recognized types of brain tumors, characterized by significant cellular and molecular diversity and an inherently aggressive nature. The treatment remains highly challenging, with limited effectiveness and persistently low survival rates.
Livia Ramos Santiago, Edgar Alejandro Pinos Tamayo, Daniel Moreira dos Santos, Bonglee Kim, José R. Almeida, Rosy Iara Maciel de Azambuja Ribeiro, Marco Eigenfeld   +6 more
wiley   +1 more source

Natural Antispasmodics: Source, Stereochemical Configuration, and Biological Activity

BioMed Research International, Volume 2018, Issue 1, 2018., 2018
Natural products with antispasmodic activity have been used in traditional medicine to alleviate different illnesses since the remote past. We searched the literature and compiled the antispasmodic activity of 248 natural compounds isolated from terrestrial plants.
Edith Fabiola Martínez-Pérez, Zaida N. Juárez, Luis R. Hernández, Horacio Bach, Juergen Buenger   +4 more
wiley   +1 more source

Edema Induced by sPLA2 from Crotalus durissus terrificus Involves PLC and PKC Signaling, Activation of cPLA2, and Oxidative Stress [PDF]

, 2019
sPLA2 from Crotalus durissus terrificus venom, free of crotapotin (Cdt sPLA2), purified and isolated sPLA2, was able to significantly increase lipid peroxidation, which occurred simultaneously with increased arachidonic acid (AA) metabolism. In addition,
Belchor, Mariana N., Costa, Caroline R.C., de Oliveira, Marcos A., Gaeta, Henrique Hessel, Ie, Rolando, Novaes, Danielle P., Toyama, Daniela de O., Toyama, Marcos H.   +7 more
core   +2 more sources

The Proteome of African Spitting and Non‐Spitting Cobra Venoms and Cytotoxicity Against Pancreatic Cancer Cells

Journal of Applied Toxicology, Volume 45, Issue 10, Page 2055-2067, October 2025.
ABSTRACT African cobra (Naja spp.) venom contains toxins dominated by proteins and peptides with inter‐ and intra‐specific variations. There are several FDA‐approved drugs from snake venom toxins from other regions, including South America and Asia. Profiling the proteomes of medically important African cobra venoms from different locations will aid in
Benedict C. Offor, Beric Muller, Lesetja R. Motadi, Lizelle A. Piater   +3 more
wiley   +1 more source

Acidentes por serpentes Crotalus durisssus ssp em crianças em Campinas, São Paulo, Brasil [PDF]

, 2002
From January, 1984 to March, 1999, 31 children under 15 y old (ages 1-14 y, median 8 y) were admitted after being bitten by rattlesnakes (Crotalus durissus ssp). One patient was classified as "dry-bite", 3 as mild envenoming, 9 as moderate envenoming and
BARACAT, Emílio Carlos Elias, BUCARETCHI, Fábio, HERRERA, Sílvia Regina Fontoura, HYSLOP, Stephen, VIEIRA, Ronan José   +4 more
core   +3 more sources

Host species and age‐specific variation on Hepatozoon prevalence and its effect on body condition in two Neotropical crocodiles

Wildlife Biology, Volume 2025, Issue 5, September 2025.
Many populations of species belonging to the order Crocodilia are threatened due to illegal trafficking, indiscriminate hunting, and habitat loss and degradation affecting crocodilian health and parasitic load. Although several studies have revealed that crocodiles, caimans, and alligators are frequently infected by Hepatozoon spp., the results from ...
Alfonso Marzal, Wendy Flores‐Saavedra, Sergio Magallanes, Jaime Muriel, Jefferson Lezama‐Briceño, Luis Alberto García‐Ayachi, Esteban Fong, Carlos Mora‐Rubio, Carlos Mendoza, Blanca Saldaña, Alazne Díez‐Fernández, José Martin, Carlos Marcial Perea‐Sicchar, Manuel González‐Blázquez   +13 more
wiley   +1 more source

Caracterización toxinológica del veneno total de la serpiente de cascabel crotalus durissus cumanenses (viperidae), presente en la localidad de porshoure, guajira venezolana

Revista Científica, 2010
En el presente trabajo se caracterizó toxinológicamente el veneno total de la serpiente de cascabel Crotalus durissus cumanenses presente en la localidad de Porshoure, Guajira venezolana, determinando: dosis letal cincuenta (DL50), actividad hemorrágica,
Rafael del Carmen Pirela De las Salas, Juan Carlos López Jonsthon, Jim Lenrry Hernández Rangel   +2 more
doaj  

Bothropic and crotalic venoms: main aspects and derivative products for therapeutic and diagnostic purposes - a brief approach / Venenos botrópicos e crotálicos: principais aspectos e produtos derivados para fins terapêuticos e diagnósticos - uma breve abordagem [PDF]

, 2022
 Ophidian accidents, mainly by snakes of the Bothrops and Crotalus genera, are an important public health problem, especially in tropical countries due to the high rate of occurrence and lethality, being considered as a neglected disease and with ...
Carvalho, Maria das Graças, Duarte, Rita Carolina Figueiredo, Nogueira, Leilismara Sousa, Nunes, Natália Ribeiro, Pinheiro, Melina de Barros   +4 more
core  

Prey specificity of predatory venoms

Biological Reviews, Volume 99, Issue 6, Page 2253-2273, December 2024.
ABSTRACT Venom represents a key adaptation of many venomous predators, allowing them to immobilise prey quickly through chemical rather than physical warfare. Evolutionary arms races between prey and a predator are believed to be the main factor influencing the potency and composition of predatory venoms.
Ondřej Michálek, Glenn F. King, Stano Pekár   +2 more
wiley   +1 more source