Results 81 to 90 of about 3,278 (198)

Bothropic and crotalic venoms: main aspects and derivative products for therapeutic and diagnostic purposes - a brief approach / Venenos botrópicos e crotálicos: principais aspectos e produtos derivados para fins terapêuticos e diagnósticos - uma breve abordagem [PDF]

, 2022
 Ophidian accidents, mainly by snakes of the Bothrops and Crotalus genera, are an important public health problem, especially in tropical countries due to the high rate of occurrence and lethality, being considered as a neglected disease and with ...
Carvalho, Maria das Graças, Duarte, Rita Carolina Figueiredo, Nogueira, Leilismara Sousa, Nunes, Natália Ribeiro, Pinheiro, Melina de Barros   +4 more
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EVALUATION OF THE ANTIBACTERIAL ACTIVITY OF Crotalus durissus terrificus CRUDE VENOM [PDF]

Ciência Animal Brasileira, 2018
Abstract Snake venoms are recognized as a promising source of pharmacologically active substances and are potentially useful for the development of new antimicrobial drugs. This study aimed to investigate the antimicrobial activity of the venom from the rattlesnake Crotalus durissus terrificus against several bacteria.
do Carmo Dietz, Jefferson, Andrade de Almeida, Daniela, Cardoso Cintra, Lorena, Rodrigues de Oliveira, Bruno Francesco, Regina Magalhães, Marta, Santos Amorim Jesuíno, Rosália   +5 more
openaire   +2 more sources

Kinetic characterization of gyroxin, a serine protease from Crotalus durissus terrificus venom

Biochimie, 2012
This work describes for the first time the characterization of the enzymatic features of gyroxin, a serine protease from Crotalus durissus terrificus venom, capable to induce barrel rotation syndrome in rodents. Measuring the hydrolysis of the substrate ZFR-MCA, the optimal pH for proteolytic cleavage of gyroxin was found to be at pH 8.4.
Yonamine, Camila Miyagui UNIFESP, Kondo, Marcia Yuri UNIFESP, Juliano, Maria Aparecida UNIFESP, Icimoto, Marcelo Yudi UNIFESP, Baptista, Gandhi R., Yamane, Tetsuo, Oliveira, Vitor UNIFESP, Juliano, Luiz UNIFESP, Lapa, Antonio José UNIFESP, Lima-Landman, Maria Teresa Riggio de UNIFESP, Hayashi, Mirian Akemi Furuie UNIFESP   +10 more
openaire   +3 more sources

Antivenenos ofídicos: comparación del desempeño de dos métodos de obtención [PDF]

, 2013
El envenenamiento por serpientes venenosas es frecuente en algunas zonas de Argentina, particularmente en las provincias del noreste y noroeste. Según datos del Programa Nacional de Ofidismo, el número de mordeduras es de alrededor de 1.200 anuales; son ...
Cascone, Osvaldo, de Marco, María Belén, Dokmetjian, José Christian, Fingermann, Matias, Iácono, Rubén, Temprano, Guillermo Carlos, Ávila, Lucía   +6 more
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Discovery of a Dicephalic Western Diamondback Rattlesnake, Crotalus atrox (Serpentes: Viperidae), from Texas, with a Summary of Dicephalism Among Members of the Genus Crotalus [PDF]

, 2006
We document the fourth record of a dicephalic western diamondback rattlesnake, Crotalus atrox, collected on 17 September 2005 in Tom Green County, Texas, along with features of its external and internal anatomy, which are compared with normal C.
McAllister, Chris T., Wallach, Van
core   +1 more source

South American Rattlesnake (Crotalus durissus spp.) Envenomation in Dogs in the Semiarid Region of Brazil [PDF]

, 2020
Background:  South American rattlesnake (Crotalus durissus spp.) envenomation is rarely reported in small animals and livestock in Brazil. Minor swelling at the snakebite site, skeletal muscle, and renal damage, and severe neurological signs characterize
Almeida Pessoa, André Flávio, Botelho de Castro, Márcio, de Macêdo Pessoa, Clarice Ricardo, de Souza Mendes, Rodrigo, Machado, Mizael, Medeiros Dantas, Antônio Flávio, Riet-Correa, Franklin, Trindade de Medeiros, Rosane Maria   +7 more
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Integrated “omics” profiling indicates that miRNAs are modulators of the ontogenetic venom composition shift in the Central American rattlesnake, [PDF]

, 2013
Background Understanding the processes that drive the evolution of snake venom is a topic of great research interest in molecular and evolutionary toxinology. Recent studies suggest that ontogenetic changes in venom composition are genetically controlled
Angulo, Yamileth, Bonilla, Fabián, Calvete, Juan J., Chacón, Danilo, Durbán, Jordi, Gutiérrez, José M., Gómez, Aarón, Pérez, Alicia, Rodríguez, Santos, Sanz, Libia, Sasa, Mahmood   +10 more
core   +2 more sources

Using DM43 and DM64, two antitoxins from didelphidae, to study the snake venon sub-proteoms [PDF]

, 2009
Comunicaciones a ...
Perales, Jonas
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Crotoxin from Crotalus durissus terrificus venom: In vitro cytotoxic activity of a heterodimeric phospholipase A2 on human cancer-derived cell lines [PDF]

, 2018
Accepted manuscriptCrotoxin (CTX), a heterodimeric phospholipase present in venom of snakes of the genus Crotalus, has demonstrated a broad spectrum of pharmacological properties, such as antimicrobial, hemostatic, and antitumoral.
Caetano, Guilherme Ferreira, de Macedo, Luana Henrique, Mazzi, Mauricio Ventura, Muller, Silvana Pinotti, Reis, R. M., Silva, Viviane Aline Oliveira, Silvestrini, Ana Vitória Pupo   +6 more
core   +1 more source

Camelid Single-Domain Antibodies (VHHs) against Crotoxin: A Basis for Developing Modular Building Blocks for the Enhancement of Treatment or Diagnosis of Crotalic Envenoming

Toxins, 2018
Toxic effects triggered by crotalic envenoming are mainly related to crotoxin (CTX), composed of a phospholipase A2 (CB) and a subunit with no toxic activity (CA).
Marcos B. Luiz, Soraya S. Pereira, Nidiane D. R. Prado, Naan R. Gonçalves, Anderson M. Kayano, Leandro S. Moreira-Dill, Juliana C. Sobrinho, Fernando B. Zanchi, André L. Fuly, Cleberson F. Fernandes, Juliana P. Zuliani, Andreimar M. Soares, Rodrigo G. Stabeli, Carla F. C. Fernandes   +13 more
doaj   +1 more source