Results 61 to 70 of about 3,278 (198)

Animal Venoms as Peptide Libraries for the Discovery of Antiglioblastoma Agents

Biochemistry Research International, Volume 2026, Issue 1, 2026.
Glioblastoma is one of the most aggressive and widely recognized types of brain tumors, characterized by significant cellular and molecular diversity and an inherently aggressive nature. The treatment remains highly challenging, with limited effectiveness and persistently low survival rates.
Livia Ramos Santiago, Edgar Alejandro Pinos Tamayo, Daniel Moreira dos Santos, Bonglee Kim, José R. Almeida, Rosy Iara Maciel de Azambuja Ribeiro, Marco Eigenfeld   +6 more
wiley   +1 more source

Natural Antispasmodics: Source, Stereochemical Configuration, and Biological Activity

BioMed Research International, Volume 2018, Issue 1, 2018., 2018
Natural products with antispasmodic activity have been used in traditional medicine to alleviate different illnesses since the remote past. We searched the literature and compiled the antispasmodic activity of 248 natural compounds isolated from terrestrial plants.
Edith Fabiola Martínez-Pérez, Zaida N. Juárez, Luis R. Hernández, Horacio Bach, Juergen Buenger   +4 more
wiley   +1 more source

The Proteome of African Spitting and Non‐Spitting Cobra Venoms and Cytotoxicity Against Pancreatic Cancer Cells

Journal of Applied Toxicology, Volume 45, Issue 10, Page 2055-2067, October 2025.
ABSTRACT African cobra (Naja spp.) venom contains toxins dominated by proteins and peptides with inter‐ and intra‐specific variations. There are several FDA‐approved drugs from snake venom toxins from other regions, including South America and Asia. Profiling the proteomes of medically important African cobra venoms from different locations will aid in
Benedict C. Offor, Beric Muller, Lesetja R. Motadi, Lizelle A. Piater   +3 more
wiley   +1 more source

Caracterización toxinológica del veneno total de la serpiente de cascabel crotalus durissus cumanenses (viperidae), presente en la localidad de porshoure, guajira venezolana

Revista Científica, 2010
En el presente trabajo se caracterizó toxinológicamente el veneno total de la serpiente de cascabel Crotalus durissus cumanenses presente en la localidad de Porshoure, Guajira venezolana, determinando: dosis letal cincuenta (DL50), actividad hemorrágica,
Rafael del Carmen Pirela De las Salas, Juan Carlos López Jonsthon, Jim Lenrry Hernández Rangel   +2 more
doaj  

Cytoskeleton, endoplasmic reticulum and nucleus alterations in CHO-K1 cell line after Crotalus durissus terrificus (South American rattlesnake) venom treatment

Journal of Venomous Animals and Toxins including Tropical Diseases, 2007
Snake venoms are toxic to a variety of cell types. However, the intracellular damages and the cell death fate induced by venom are unclear. In the present work, the action of the South American rattlesnake Crotalus durissus terrificus venom on CHO-K1 ...
B. P. Tamieti, R. A. Damatta, J. C. Cogo, N. S. Da Silva, J. Mittmann, C. Pacheco-Soares   +5 more
doaj   +1 more source

Snake venomics and antivenomics of Middle and South America rattlesnakes.Identification of neurotoxin crotoxin as an adaptive trait during Crotalus Durissus invasion of South America [PDF]

, 2009
Comunicaciones a ...
Alape-Girón, Alberto, Calvete, Juan J., Escolano, José, Flores-Díaz, Marietta, Gutiérrez, J.M., Sanz, Libia, Sasa, Mahmood   +6 more
core  

Fractal Dimension in Liver Histological Findings of Wistar Rats Experimentally Intoxicated with Venom of Crotalus durissus terrificus [PDF]

, 2019
Background: Accidents caused by venom of Crotalus durissus snakes, popularly known in Brazil as rattlesnake, are second in relation to the occurrence and first place in deaths in humans and animals, mainly due to the great neurotoxic, myotoxic, coagulant,
de Brito, Adriana Falco, de Melo, Gabriela Haro, Izique Goiozo, Paulo Felipe, Nogueira, Rosa Maria Barilli, Pereira, Cristiane de Pauli, Saneshigue dos Santos, Isabella Keyko Navarro   +5 more
core   +3 more sources

Host species and age‐specific variation on Hepatozoon prevalence and its effect on body condition in two Neotropical crocodiles

Wildlife Biology, Volume 2025, Issue 5, September 2025.
Many populations of species belonging to the order Crocodilia are threatened due to illegal trafficking, indiscriminate hunting, and habitat loss and degradation affecting crocodilian health and parasitic load. Although several studies have revealed that crocodiles, caimans, and alligators are frequently infected by Hepatozoon spp., the results from ...
Alfonso Marzal, Wendy Flores‐Saavedra, Sergio Magallanes, Jaime Muriel, Jefferson Lezama‐Briceño, Luis Alberto García‐Ayachi, Esteban Fong, Carlos Mora‐Rubio, Carlos Mendoza, Blanca Saldaña, Alazne Díez‐Fernández, José Martin, Carlos Marcial Perea‐Sicchar, Manuel González‐Blázquez   +13 more
wiley   +1 more source

Treatment of Snake Bites at a Regional Burn Center: Report of a Case Series [PDF]

, 2013
Background. Although uncommon, snakebites can cause significant morbidity and mortality. The objective of this study was to review the characteristics, treatment, and outcome of patients with a suspected or known snakebite who were treated at a regional ...
Helmer, Stephen D, Khandelwal, Anjay K, Yu, Gie N   +2 more
core   +2 more sources

Prey specificity of predatory venoms

Biological Reviews, Volume 99, Issue 6, Page 2253-2273, December 2024.
ABSTRACT Venom represents a key adaptation of many venomous predators, allowing them to immobilise prey quickly through chemical rather than physical warfare. Evolutionary arms races between prey and a predator are believed to be the main factor influencing the potency and composition of predatory venoms.
Ondřej Michálek, Glenn F. King, Stano Pekár   +2 more
wiley   +1 more source