Results 101 to 110 of about 631,469 (197)
ABSTRACT Background Allergic rhinitis (AR) represents a highly prevalent inflammatory disorder of the nasal mucosa, but molecular indicators capable of capturing its disease‐specific transcriptional features remain insufficiently defined. This study aimed to identify cell adhesion‐related diagnostic biomarkers for AR and to investigate their immune ...
Guoshun He, Liying Zhang
wiley +1 more source
Molecular and Cellular Underpinnings of Primary Hypertension: An Integrative Mechanistic Framework
ABSTRACT Hypertension is a highly prevalent clinical condition and a major contributor to global cardiovascular morbidity and mortality. Despite extensive research, its complex and multifaceted pathogenesis is yet to be fully elucidated. This paper explores the updated understanding of primary hypertension as a systemic disorder rather than an isolated
Dima Nasrallah +5 more
wiley +1 more source
Tillage Options After CRP [PDF]
In making tillage decisions for CRP land, consider conservation concerns, farming objectives, and plant and soil conditions. This publication provides research results to help you.
Sternweis, Laura +6 more
core
Abstract Deoxyuridine triphosphatase (dUTPase) is essential for DNA replication fidelity and embryonic development in metazoa, yet whether a protein inhibitor can acutely disrupt dUTPase function in a living vertebrate has not been tested. The Staphylococcus aureus Stl protein inhibits diverse dUTPases in vitro, but its efficacy in a eukaryotic ...
Viktória Perey‐Simon +7 more
wiley +1 more source
Background: Rheumatoid arthritis (RA) is a systemic, chronic autoimmune condition characterized by joint inflammation and pain, leading to the degeneration of the joints and bones, which may develop into deformities.
Furqan Hasan Razzaq, Rana Fadhil Obaid
doaj +1 more source
ABSTRACT Aims To investigate the association between serum ALP levels and the development of AKI in paediatric patients with sepsis. Methods Retrospective screening of a computerized database of 4 Israeli regional hospitals for children (0–18 years) hospitalized between 1.01.2000–1.06.2024 with ICD‐9 sepsis‐related diagnoses (study group) and age‐ and ...
Evgenia Gurevich +5 more
wiley +1 more source
The presence of c-reactive protein (CRP) isoforms during murine wound healing [PDF]
Native C reactive protein (nCRP) is a pentameric oligoprotein composed of 5 identical protomers. Levels of this acute phase protein increase up to 1000 fold with the onset of inflammation; dissociation into single subunits creates a new isoform known as ...
Hynes, Julia Sarah
core
Background Contribution of nitric-oxide (NO) pathway to the pathogenesis of bronchial asthma (asthma) is ambiguous as NO may confer both protective and detrimental effects depending on the NO synthase (NOS) isoforms, tissue compartments and underlying ...
Gabor Tajti +10 more
doaj +1 more source
ABSTRACT Aim To investigate the association between baseline plasma α‐hydroxybutyrate (α‐HB), an organic acid derived from aminoacid catabolism and glutathione anabolism, and the 10‐year incidence of Type 2 diabetes (T2DM). Materials and Methods This prospective study analysed 1349 participants from the Swedish PAROKRANK study.
Elena Fortin +5 more
wiley +1 more source
ABSTRACT Background Circadian clock disruption has emerged as a relevant axis in cancer; however, the expression patterns and diagnostic relevance of BMAL1 and CLOCK in multiple myeloma (MM) remain insufficiently defined. Methods BMAL1 and CLOCK mRNA expression was quantified by RT‐qPCR in bone marrow samples from 46 newly diagnosed MM patients and 13 ...
Hamide Albayrak +6 more
wiley +1 more source

