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Intra-subunit Disulfide Determines the Conversion and Structural Stability of CRP Isoforms
Inflammation, 2019C-reactive protein (CRP) is a major human acute-phase reactant that is composed of five identical subunits. CRP dissociates into subunits at inflammatory loci forming monomeric CRP (mCRP) with substantially enhanced activities, which can be further activated by reducing the intra-subunit disulfide bond.
Ming-Yu Wang
exaly +3 more sources
IL-6 regulates induction of C-reactive protein gene expression by activating STAT3 isoforms
Molecular Immunology, 2022Donald N Ngwa, Alok Agrawal
exaly
C-Reactive Protein Isoforms Differ in Their Effects on Thrombus Growth
Arteriosclerosis, Thrombosis, and Vascular Biology, 2008Lina Badimon +2 more
exaly
Pentameric CRP attenuates inflammatory effects of mmLDL by inhibiting mmLDL–monocyte interactions
Atherosclerosis, 2012Andrew Murphy +2 more
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Neutralization of viral infectivity by zebrafish c-reactive protein isoforms
Molecular Immunology, 2017Alberto Falco +2 more
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Association of Common CRP Gene Variants with CRP Levels and Cardiovascular Events
Annals of Human Genetics, 2005David Kwiatkowski
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