Results 181 to 190 of about 14,674 (226)

Engineered CRISPR/Cas12a2 Nanoprobe Imaging in Living Cells for Precise Tumor Diagnosis. [PDF]

Small Methods
Li J, Ji C, Yang W, Han Y, Zhao P, Cai X, Tian S, Zhu W, Zhang J, Xu J, Yang W, Li F, Liu P.   +12 more
europepmc   +1 more source

CRISPR-Cas12a-based fluorescent and visual assays for universal detection and clade discrimination of mpox virus. [PDF]

Microbiol Spectr
Mao Y, Fei X, Yang X, Hu C, Zhu C, Wang J, Ge Y, Ye C, Yang S, Cheng P, Li Y, He X, Hu Z, Qi Y.   +13 more
europepmc   +1 more source

Multimodal control of Cas13d activity through domain insertion at an allosteric hotspot. [PDF]

Nat Commun
Zhu L, Nguyen LT, Bell AG, Krebel T, Gillmann KM, Cao Q, Oatman H, Hariri J, Möglich A, Myhrvold C, Toettcher JE.   +10 more
europepmc   +1 more source

Structural mechanism of SAM-AMP and SAM-AMP₂ synthesis by the type III-D2 CRISPR effector complex. [PDF]

Nat Commun
Mitsuda Y, Sugaya M, Ishikawa J, Nagahata N, Okazaki S, Hiraizumi M, Kato K, Gootenberg JS, Abudayyeh OO, Osawa T, Yamashita K, Nishimasu H.   +11 more
europepmc   +1 more source

Production of virus-like particles with AsCas12a nuclease and CMV-driven crRNA for mammalian genome editing. [PDF]

Front Genome Ed
Kruglova NA, Borovikova SE, Shepelev MV.
europepmc   +1 more source

Guide RNA reprogramming facilitates minimized tracrRNA-dependent off-target and versatile CRISPR/Cas9 engineering. [PDF]

Nat Commun
Yu W, Chen J, Guo J, Yu F, Wang G, Lin J, Dai X, Tan X, Ma P, Wu L, Zhang Y, Huang S, Lan P, Bian Q, Huang X, Wei J, Cheng T, Zheng X, Qiao Y.   +18 more
europepmc   +1 more source

Development of an RT-LAMP-CRISPR/Cas12a-based nucleic acid detection platform for rapid diagnosis of porcine reproductive and respiratory syndrome virus type 2. [PDF]

Vet Anim Sci
Li C, Sun C, Xu Q.
europepmc   +1 more source

Multiplex RPA-CRISPR/Cas12a Assay for Rapid Detection of Class D OXA-Type Carbapenem-Resistant <i>Acinetobacter baumannii</i>. [PDF]

Biosensors (Basel)
Amanzholova M, Akimbekova A, Shaizadinova A, Sutimbekova N, Bissenova N, Tarlykov P, Abeldenov S.   +6 more
europepmc   +1 more source