Results 101 to 110 of about 318,926 (263)

Calidad de la biomasa forrajera de cinco cultivares de

Pastos y Forrajes
Objective: To evaluate the foliage quality of five cultivars of Manihot esculenta Crantz during the annual growing cycle of the crop in northeastern Argentina. Materials and Methods: Five cultivars of M.
Miriam Porta, Claudina María Hack, Angela María Burgos, Sebastián Carnicer   +3 more
doaj  

Protein Structuromics Reveals a Loop‐Controlled Half‐Open Active Pocket Conformation Throughout Fe(II)/α‐ketoglutarate‐Dependent Dioxygenase Catalytic Cycle

Advanced Science, EarlyView.
This study reveals a conserved half‐open active pocket in Fe(II)/α‐ketoglutarate‐dependent dioxygenases through protein structuromics, distinguished by structural features comprising highly flexible loop elements. Enhanced sampling simulations‐guided mutagenesis experiments elucidated how this flexible loop regulates pocket open/closed conformations ...
Lunjie Wu, Huan Liu, Songyin Zhao, Lei Qin, Jiarui Li, Jun Wang, Zixuan Dai, Jie Gu, Yan Xu, Feiran Li, Yao Nie   +10 more
wiley   +1 more source

Effects of low-protein diets supplemented with lysine on growth performance and serum indexes of piglets

Siliao yanjiu
The experiment aimed to investigate the effects of low-protein diets supplemented with lysine on the growth performance, serum biochemical indicators, antioxidant capacity, and amino acid content of piglets.
DING Xiao, ZHAO Xiaogang, GUO Jiyu, WAN Fachun   +3 more
doaj  

SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition

Advanced Science, EarlyView.
Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo, Liwei Zhang, Minlong Wang, Yanjin Du, Tianyu Zhang, Hao Chen, Jiazeng Sun, Yang Yu, Zude He, Jie An, Xiaoxu Zhang, Weilin Lin, Fazheng Ren, Pengjie Wang, Ping Liu   +14 more
wiley   +1 more source

AI‐Designed Cyclic Peptides Enable Controllable Modulation of the CD28 Immune Checkpoint

Advanced Science, EarlyView.
AI‐designed cyclic peptides enable controllable modulation of the CD28 immune checkpoint through reversible disruption of CD28‐CD80/CD86 interactions. The lead peptide, CIP‐3, suppresses T‐cell activation without intrinsic agonist activity, demonstrates dose‐dependent efficacy in a murine colitis model, and attenuates inflammatory cytokine production ...
Katarzyna Kuncewicz, Saurabh Upadhyay, Renjie Zhu, Hongliang Duan, Moustafa T. Gabr   +4 more
wiley   +1 more source

Thermally Processable, Transparent, Mechanically Tunable and Robust Bioplastics From Wastepaper

Advanced Science, EarlyView.
Unlike conventional inefficient or low‐value wastepaper recycling, a directional transformation strategy is employed to convert whole wastepaper into intact bioplastics with tunable mechanical properties in our work. These bioplastics can be processed into flexible bags or rigid containers and exhibit high transparency, water resistance, repairability,
Zhezhe Zhou, Tao Chu, Boyou Hou, Mark Lynch, Siqi Huo, Min Hong, Jianguo Yang, Paulomi (Polly) Burey, Qiang Gao, Guobo Huang, Pingan Song   +10 more
wiley   +1 more source

Molecular Mobility of N‐Acetylgalactosamine‐Modified Cyclodextrins on a Polyrotaxane for Highly Efficient Liver Targeting of Antibody Chimeras and Genome‐Editing Ribonucleoproteins

Advanced Science, EarlyView.
Monovalent N‐acetylgalactosamine (GalNAc)‐modified polyrotaxane enables efficient liver targeting by utilizing ligand mobility. The sliding and rotating cyclic components i.e., cyclodextrin in the polyrotaxane dynamically cluster GalNAc moieties, thereby mimicking trivalent interactions with asialoglycoprotein receptors.
Toru Taharabaru, Keiichi Motoyama, Yuting Wen, Zhongxing Zhang, Xuehao Tian, Jun Li, Taishi Higashi   +6 more
wiley   +1 more source

Crude Protein and Crude of Fiber Benggala [Panicum Maximum] and Elephant [Pennisetum Purpureum] Grasses on Drought Stress Condition

Animal Production: Indonesian Journal of Animal Production, 2009
Knowledge of crop response to water is essential for proper irrigation management. Research was conducted at Forage Crop Laboratory of Animal Nutrition Department, Faculty Of Animal Husbandry, Diponegoro University during 9 month trying two type ...
ED Purbajanti, S Anwar, S Widyati, F Kusmiyati   +3 more
doaj  

Microblasting Wound Dressings Mechanically Disrupt Polymicrobial Biofilms to Enhance Healing in Treatment‐Resistant Wounds

Advanced Science, EarlyView.
Treatment‐resistant wounds caused by polymicrobial biofilms are refractory to conventional therapies due to the dense extracellular matrices. We developed μBLAST, a microblasting wound dressing that combines MnO2‐doped biosilica and a H2O2‐releasing mesh to generate localized oxygen microbubbles that mechanically disrupt biofilms.
Yujin Ahn, Joo Hun Lee, Christian Hurd, Jiye Lee, Junggeon Park, Adam A. Markowicz, Zheyuan Zhang, Joanne Hwang, Guillermo L. Monroy, Simon A. Rogers, Woonggyu Jung, Stephen A. Boppart, Hyunjoon Kong   +12 more
wiley   +1 more source

Mechanistic Understanding of Protein–MOF Integration Through Surfactant‐Driven Interfacial Design

Advanced Science, EarlyView.
This study reveals how surfactant‐driven interfacial design governs the assembly and stability of protein@MOF composites. Using lipid‐based nonionic surfactants, we modulate protein–MOF interactions to improve encapsulation efficiency, MOF crystallization, and catalytic performance.
Ehsan Rashidniyaghi, Mohammad Khavani, Carlie Coerver, Ruibin Liang, Raheleh Ravanfar   +4 more
wiley   +1 more source