Results 101 to 110 of about 1,668 (161)

Inhibitors of Proteases: A Well-Grounded Strategy in Drug Development. [PDF]

Molecules
Previti S, Ettari R.
europepmc   +1 more source

The Power of Molecular Dynamics Simulations and Their Applications to Discover Cysteine Protease Inhibitors. [PDF]

Mini Rev Med Chem
Dos Santos Nascimento IJ, Gomes JNS, de Oliveira Viana J, de Medeiros E Silva YMS, Barbosa EG, de Moura RO.   +5 more
europepmc   +1 more source

Nifuroxazide and 4-Hydroxybenzhydrazone Derivatives as New Antiparasitic (<i>Trypanosoma cruzi</i> and <i>Leishmania mexicana</i>) and Anti-<i>Mycobacterium tuberculosis</i> Agents. [PDF]

Pharmaceutics
Delgado-Maldonado T, Navarrete-Carriola DV, Vázquez-Jiménez LK, Paz-González AD, Wan B, Franzblau S, Mohammed OM, Rodríguez-Páez L, Aguirre-Alvarado C, Alcántara-Farfán V, Cordero-Martínez J, Bandyopadhyay D, Moreno-Rodríguez A, Rivera G.   +13 more
europepmc   +1 more source

Anti-<i>Trypanosoma cruzi</i> Potential of New Pyrazole-Imidazoline Derivatives. [PDF]

Molecules
de Oliveira EC, Lara LDS, Orlando LMR, Lanera SDC, de Souza TP, Figueiredo NDS, Paes VB, Mazzochi AC, Fernandes PHM, Dos Santos MS, Pereira MCS.   +10 more
europepmc   +1 more source

Thiosulfonate-Based Targeted Covalent Cruzipain Inhibitors with Enhanced Bioactivity Translation for Antichagasic Therapy. [PDF]

ACS Med Chem Lett
Cerutti JP, Diniz LA, Corrêa Santos V, Vilchez Larrea SC, Alonso GD, Ferreira RS, Dehaen W, Quevedo MA.   +7 more
europepmc   +1 more source

Hits and Lead Discovery in the Identification of New Drugs against the Trypanosomatidic Infections [PDF]

, 2019
Ana Isabel Olías-Molero, Anabela Cordeiro da Silva and José María Alunda, George E. Magoulas, Ina Pöhner, Joanna Panecka-Hofman, Ma Dolores Jiménez-Antón, Maria Paola Costi, Nuno Santarem, Pasquale Linciano, Rebecca C. Wade, Stefania Ferrari, Theodora Calogeropoulou   +11 more
core   +1 more source

Combining Charge Density Analysis with Machine Learning Tools To Investigate the Cruzain Inhibition Mechanism

ACS Omega, 2019
Adriano M. Luchi, Roxana N. Villafañe, J. Leonardo Gómez Chávez, M. Lucrecia Bogado, Emilio L. Angelina, Nelida M. Peruchena   +5 more
doaj   +1 more source

Pyrazole-Imidazoline Derivative Prevents Cardiac Damage and Mortality in Acute <i>Trypanosoma cruzi</i> Infection. [PDF]

Pharmaceuticals (Basel)
Orlando LMR, Lara LDS, de Souza TP, Paes VB, Calvet CM, de Mesquita LB, Lechuga GC, Pereira CN, Dos Santos MS, Pereira MCS.   +9 more
europepmc   +1 more source

Discovery of benzyl carbamate inhibitors of coronavirus M^pro enzymes from a legacy collection of cysteine protease inhibitors. [PDF]

J Enzyme Inhib Med Chem
Sá Magalhães Serafim M, Kronenberger T, Francisco KR, de Sousa Reis EV, Gonçalves de Oliveira E, Marcelino E Oliveira FK, Serraglio Fortes I, Maciel Fernandes TH, Barbosa da Silva E, Fajtova P, Skinner DE, Syed RO, Lage de Siqueira-Neto J, Poso A, Fernandes Mota BE, Alves Coelho-Dos-Reis JG, Santos Abrahão J, Gonçalves Maltarollo V, O'Donoghue AJ, Caffrey CR.   +19 more
europepmc   +1 more source

Structure Elucidation, Biosynthetic Gene Cluster Distribution, and Biological Activities of Ketomemicin Analogs in <i>Salinispora</i>. [PDF]

Mar Drugs
Castro-Falcón G, Guillén-Matus DG, Silva EBD, Guo W, Ross A, Sá Magalhães Serafim M, Fernandes THM, Tantillo DJ, O'Donoghue AJ, Jensen PR.   +9 more
europepmc   +1 more source