Investigation of Cruzain Inhibition by Thiosemicarbazone Compounds
, 2018 Chagas disease, the result of infection by the protozoan parasite Trypanosoma cruzi, is transmitted by blood-feeding insect vectors that are members of the Reduviidae family called kissing bugs.
Lill, Isaac, Lill, Isaac.
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Haemanthidine-Containing Alkaloid Fraction from <i>Crinum scabrum</i> as a Natural Therapeutics for Chagas Disease. [PDF]
ACS OmegaPardo JB +7 more
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Antiparasitic Activities of Compounds Isolated from Aspergillus fumigatus Strain Discovered in Northcentral Nigeria. [PDF]
Antibiotics (Basel), 2023 Diyaolu OA +10 more
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Investigation of the activity of 4-aminoquinolines as cysteine protease inhibitors with application in the treatment of Chagas disease. [PDF]
Mem Inst Oswaldo CruzSheu-Idrees R +10 more
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Nitriles: an attractive approach to the development of covalent inhibitors. [PDF]
RSC Med Chem, 2023 Bonatto V +5 more
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Similarity-Based Profiling of Hydrazone-Containing Scaffolds Active Against <i>Leishmania</i> Amastigotes. [PDF]
ACS OmegaPereira da Silva RY +5 more
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Unraveling Common Patterns and Differences among Cruzipains through Molecular Dynamics Simulations and Structural Analyses. [PDF]
ACS OmegaSantos LHS +5 more
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Self-Masked Aldehyde Inhibitors: A Novel Strategy for Inhibiting Cysteine Proteases. [PDF]
J Med Chem, 2021 Li L +24 more
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Recent Progress in Thiazole, Thiosemicarbazone, and Semicarbazone Derivatives as Antiparasitic Agents Against Trypanosomatids and <i>Plasmodium</i> spp. [PDF]
MoleculesSouza Tada da Cunha P +4 more
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TrypPROTACs Unlocking New Therapeutic Strategies for Chagas Disease. [PDF]
Pharmaceuticals (Basel)Rodriguez Gini AL +6 more
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