Results 201 to 210 of about 132,225 (219)

Integrating Cryo-Electron Microscopy and Molecular Dynamics Simulations to Investigate Membrane Binding of Influenza Virus Fusion Peptides. [PDF]

J Am Chem Soc
Setny P, Borkowska P, Worch R.
europepmc   +1 more source

Automated Bacterial Identification and Morphological Feature Analysis in Low‐Dose Cryo‐EM Using YOLOv11

Advanced Intelligent Discovery, EarlyView.
AI‐based tools enable rapid characterization of bacterial ultrastructure in low‐dose cryogenic transmission electron microscopy. The envelope thickness tool quantifies membrane thickness and anisotropy. The flagella module analyzes filament morphology and detects cell‐flagella contacts.
Sita Sirisha Madugula, Lynnicia N. Massenburg, Spenser R. Brown, Amber N. Bible, Chanda R. Harris, Lance X. Zhang, Kiara Parker, Scott T. Retterer, Jennifer L. Morrell‐Falvey, Rama K. Vasudevan, Alexis N. Williams   +10 more
wiley   +1 more source

Cryo-Electron Microscopy of BfpB Reveals a Type IVb Secretin Multimer Adapted to Accommodate the Exceptionally Wide Bundle-Forming Pilus. [PDF]

Pathogens
Little JI, Singh PK, Samsó M, Donnenberg MS.   +3 more
europepmc   +1 more source

Open and closed structures of L-arginine oxidase by cryo-electron microscopy and X-ray crystallography. [PDF]

J Biochem
Yamaguchi H, Takahashi K, Numoto N, Suzuki H, Tatsumi M, Kamegawa A, Nishikawa K, Asano Y, Mizukoshi T, Miyano H, Fujiyoshi Y, Sugiki M.   +11 more
europepmc   +1 more source

Local structural dynamics of Rad51 protomers revealed by cryo-electron microscopy of Rad51-ssDNA filaments. [PDF]

Nucleic Acids Res
Liu J, Gore SK, Heyer WD.
europepmc   +1 more source

Trisoxazole Macrolides Potentiate the Microtubule Assembly and Antimitotic Activities of Taxanes

Angewandte Chemie, EarlyView.
Photoaffinity experiments identified tubulin as a new target of mycalolides. Though weakly cytotoxic, the trisoxazole macrolactone moiety enhanced paclitaxel's microtubule assembly and antimitotic effects. Molecular modeling studies suggested that MyC stabilizes α/β‐tubulin heterodimer interactions.
Shohei Ebihara, Rio Takaiso, Shota Kawaguchi, Atsunori Oshima, Masaki Kita   +4 more
wiley   +1 more source

Cryo-Electron Microscopy Provides Mechanistic Insights into Solution-Dependent Polymorphism and Cross-Aggregation Phenomena of the Human and Rat Islet Amyloid Polypeptides. [PDF]

Biochemistry
Valli D, Ooi SA, Kaya I, Thomassen AB, Chaudhary H, Weidner T, Andrén PE, Maj M.   +7 more
europepmc   +1 more source

Macromolecular Condensates as Tunable Scaffolds for Bio‐Inspired Silica Hybrids

Angewandte Chemie, EarlyView.
Dense bio‐inspired silica formation is achieved by coupling polyamine liquid–liquid phase separation with pH‐dependent silica polymerization. Silicification within polyamine condensates, enables precise control over particle size, density, and morphology.
Protap Biswas, Lior Aram, Nitzan Livni, Roman Kamyshinsky, Nadav Elad, Michal Leskes, Assaf Gal   +6 more
wiley   +1 more source

Aggregation dynamics of a 150 kDa Aβ42 oligomer: Insights from cryo electron microscopy and multimodal analysis. [PDF]

Comput Struct Biotechnol J
Kamalaldinezabadi SS, Watzlawik JO, Rosenberry TL, Paravastu AK, Stagg SM.   +4 more
europepmc   +1 more source