Cryo-EM structures of higher order Gephyrin oligomers reveal principles of inhibitory postsynaptic scaffold organization. [PDF]
Ortiz-López D +12 more
europepmc +1 more source
Tetrazine Functionalized Graphene Enables Capture of Ultra‐Low Concentrations of Biomacromolecules
A novel method for covalent modification of monolayer graphene utilizing tetrazine containing diazonium salt is demonstrated. The modified graphene bearing tetrazine moieties undergoes inverse electron demand Diels‐Alder reactions with trans‐cyclooctene‐linked molecules, enabling bioorthogonal attachment of nanobodies that selectively capture EGFP ...
Ravindra K. Gupta +4 more
wiley +1 more source
Cryo-EM structures of human P2X2/3 heteromer channel reveal the structural basis of ligand selectivity. [PDF]
Cheng X +8 more
europepmc +1 more source
Compostable and Recyclable Baroplastic Triblock Copolymers Enable Low‐Energy Polymer Processing
Baroplastic Poly(L‐lactide)‐block‐poly(ethylene glycol)‐block‐poly(L‐lactide) triblock copolymers enable ambient‐temperature processing under moderate pressure, reducing energy demand while preserving polymer integrity. The materials show rapid industrial compostability, effective chemical and physical recyclability, and compatibility with heat ...
Chengzhang Xu +12 more
wiley +1 more source
Connecting the dots: deep learning-based automated model building methods in cryo-EM. [PDF]
Bansia H, des Georges A.
europepmc +1 more source
SERS‐Based Nano‐ and Microsystems Toward Biomedical Applications
This review provides a current overview of nano‐ and microscale SERS‐based devices, encompassing all aspects from material design to practical applications. We highlight controlled SERS‐active architectures, including patterned substrates, nanorods, microspheres, micromotors, and microneedles, as well as combinations of these microfluidic systems.
Gohar Soufi +14 more
wiley +1 more source
Cryo-EM structures of human ClpXP reveal mechanisms of assembly and proteolytic activation. [PDF]
Chen W, Lander GC, Yang J.
europepmc +1 more source
Macromolecular crystallography at Elettra: current and future perspectives. Corrigendum
Corrigendum to the article by Hegde et al. [(2025). J. Synchrotron Rad.32, 757–765].Corrigendum to the article by Hegde et al. [(2025). J. Synchrotron Rad.32, 757–765].
Raghurama P. Hegde +13 more
wiley +1 more source
Microsecond Time-Resolved Cryo-EM Based on Jet Vitrification
Haubner M +7 more
europepmc +1 more source

