Results 231 to 240 of about 99,841 (293)

Point cloud deformation modeling for particle selection following cryo-EM 2D classification. [PDF]

BMC Bioinformatics
Wang X, Mo Z, Li F, Zhang F, Wan X.
europepmc   +1 more source

Comprehensive transduceromic profiling of NOP receptor ligands at different Gα subunits

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose The nociceptin/orphanin FQ (N/OFQ) peptide receptor (NOP) is an opioid receptor family member with distinct pharmacology and broad therapeutic potential. NOP receptors regulate functions such as nociception, stress reactivity, reward, mood, autonomic tone, immunity and sleep/wake cycle.
Davide Malfacini, Riccardo Camilotto, Michele Maritan, Erika Morrone, Stephen Afriyie Boateng, Anna Vacilotto, Salvatore Pacifico, Remo Guerrini, Nurulain T. Zaveri, Girolamo Calo'   +9 more
wiley   +1 more source

CryoWriter: A Robotic Solution for Improved Cryo-EM Grid Preparation

Chinmaya K, Ekundayo B, Di Fabrizio M, Mohammed I, Radecke J, Stahlberg H, Kube M.   +6 more
europepmc   +1 more source

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking. [PDF]

Brief Bioinform
Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q.   +7 more
europepmc   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Cryo-EM Structures of Alcohol Oxidase Isozymes Reveal Structural Determinants of Cofactor Variation and Enzymatic Activity in Ogataea methanolica. [PDF]

Microb Biotechnol
Cai HL, Shimada A, Hamaguchi T, Mizoguchi A, Yonekura K, Tsuchiyama K, Shimada M, Ebihara A, Tani K, Nakagawa T.   +9 more
europepmc   +1 more source

A method for cryo-EM analysis of eukaryotic nucleosomes reconstituted in bacterial cells. [PDF]

iScience
Ho CH, Kobayashi Y, Ogasawara M, Takizawa Y, Kurumizaka H.   +4 more
europepmc   +1 more source

Reversible lipid-mediated pH-gating of connexin-46/50 by cryo-EM. [PDF]

Nat Commun
Jarodsky JM, Myers JB, Reichow SL.
europepmc   +1 more source

Cryo-EM reveals multiple mechanisms of ribosome inhibition by doxycycline

Stuart WS, Isupov MN, McLaren M, Jenkins CH, Monier A, Daum B, Norville IH, Gold VA, Harmer NJ.   +8 more
europepmc   +1 more source

Cryo-EM structures of UBA6 reveal mechanisms of E1-E2 specificity and dual FAT10/ubiquitin thioester transfer. [PDF]

Nat Commun
Nayak D, Jia L, Dos Santos Bury P, Ruben EA, Shukla A, Nayak A, Stratton CM, Ebadi P, Cho H, Tumanova AA, Varughese JT, Yuan L, Gao F, Cano KE, Davies C, Sung P, Gack MU, Wasmuth EV, Olsen SK.   +18 more
europepmc   +1 more source