Results 221 to 230 of about 6,313,615 (343)

Step-by-step maturation mechanism of the binary toxin pore revealed by cryo-EM analysis. [PDF]

open access: yesProc Natl Acad Sci U S A
Yamada T   +6 more
europepmc   +1 more source

DNA Nanotechnology Meets Peptide and Protein Self‐Assembly

open access: yesChemistry – A European Journal, EarlyView.
Combining DNA nanotechnology with peptide and protein assembly provides complementary platforms for the rational engineering of functional biomaterials. This Perspective discusses the emerging field of self‐assembling DNA‐peptide and DNA‐protein hybrid systems that combine the structural precision and programmability of DNA nanotechnology with the ...
Marcel Hanke   +4 more
wiley   +1 more source

Cryo-EM Analysis in CASP16. [PDF]

open access: yesProteins
Mulvaney T, Kryshtafovych A, Topf M.
europepmc   +1 more source

Trends and Future Directions in Organic Chemistry for Drug Discovery

open access: yesChemistry – A European Journal, EarlyView.
Organic synthesis is being reshaped by the convergence of catalytic innovation, automation, artificial intelligence, and emerging therapeutic modalities. Late‐stage functionalization, photoredox and electrochemical methods, biocatalysis, flow chemistry, DELs, and proximity‐based drugs are examined as components of closed‐loop discovery.
Paweł Kozyra, Maciej Masłyk
wiley   +1 more source

Cryo-EM structure of a 95-base-pair double-stranded DNA minicircle at 5.3 Å resolution. [PDF]

open access: yesNucleic Acids Res
Liu Y   +7 more
europepmc   +1 more source

A Low‐Oxidation‐State Mechanism for O─O Bond Formation in Photosystem II via Oxo–Hydroxyl Radical Coupling

open access: yesChemistry – A European Journal, EarlyView.
An oxo–hydroxyl radical coupling mechanism is identified for O─O bond formation in Photosystem II within the low‐oxidation‐state paradigm. Ca‐bound W3 forms Ox in the S4 state and subsequently couples with O5. The resulting hydroperoxide intermediate provides a mechanistic explanation for the poor resolution of Ox in XFEL structures.
Alireza Ariafard   +2 more
wiley   +1 more source

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