Results 101 to 110 of about 166,403 (367)

Effect of recombinant human vascular endothelial growth factor on testis tissue xenotransplants from prepubertal boys: a three-case study [PDF]

, 2019
Research question Does recombinant human vascular endothelial growth factor (VEGF-165) improve the efficiency of human immature testis tissue (ITT) xenotransplantation?
Goossens, Ellen, Kadam, Prashant, Ntemou, Elissavet, Van Laere, Sven, Van Saen, Dorien, Vicini, Elena   +5 more
core   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

Apoptotic Cell Death and Function of Cryopreserved Porcine Hepatocytes in a Bioartificial Liver

Cell Transplantation, 2003
We have previously shown that cryopreservation leads to increased apoptotic death of porcine hepatocytes intended for use in a bioartificial liver (BAL).
Takakazu Matsushita, Toshikazu Yagi, Joseph A. Hardin, Jennifer D. Cragun, Frank W. Crow, H. Robert Bergen, Gregory J. Gores, Scott L. Nyberg M.D., Ph.D.   +7 more
doaj   +1 more source

REVIEW: Current Status of Extenders and Cryoprotectants on Fish Spermatozoa Cryopreservation [PDF]

, 2005
An important component of many studies of cryopreservation of fish spermatozoa is the type of extenders and cryoprotectants. The suitability of extenders and cryoprotectants differs from one fish to another.
Z.A, Muchlisin
core  

The effect of repeated cryopreservation and thawing using cryotip on the clinical outcomes of embryos [PDF]

, 2021
Yamato Mizobe, Yukari Kuwatsuru, Yuko Kuroki, Yumiko Fukumoto, Mari Tokudome, Harue Moewaki, Mia Watanabe, Tatsunori Tabira, Tokiko Iwakawa, Kazuhiro Takeuchi   +9 more
openalex   +1 more source

5‐Hydroxymethylcytosine Dynamics Reveals Coordinated Reprogramming of Parental Genomes and X Chromosome Dosage Balance in Mouse SCNT Embryos

Advanced Science, EarlyView.
Genome‐wide, high‐resolution profiling of hydroxymethylation in mouse SCNT embryos reveals a transient, allele‐symmetric 5hmC reprogramming pattern distinct from natural embryos, with X‐chromosomes and imprinting control regions resistant to proper remodeling.
Zeming Xiang, Rui Yan, Jing Guo, Mengyao Wang, Xin Cheng, Fan Zhang, Tianzi Guo, Xin Long, Fan Guo, Dan Liang   +9 more
wiley   +1 more source

MODELING OF THE KINETICS OF CRYOGENIC FREEZING OF LIMA BEAN SEEDS AS A FUNCTION OF INITIAL WATER CONTENT [PDF]

Engenharia Agrícola
Cryopreservation is a technique used to preserve genetic material at ultra-low temperatures in cryogenic germplasm banks. In order to enable the cryopreservation of a seed, it is necessary to study its appropriate freezing temperature and its water ...
Karina M da F. Luciano, Mario E. R. M. Cavalcanti Mata, Mauri Fortes, Maria E. M. Duarte   +3 more
doaj   +2 more sources

Targeting the SOX9/TIMP1 Axis with iRGD‐Conjugated Nanoplatform Enhances Dendritic Cell Function and Photodynamic Immunotherapy in Gastric Cancer

Advanced Science, EarlyView.
This study identifies the SOX9/TIMP1 axis as a key regulator of immune evasion in gastric cancer. iRGD‐conjugated nanoparticles co‐delivering si‐SOX9, Ce6, and L‐Arg are developed to synergize with photodynamic therapy. The nanoplatform suppresses tumor growth, promotes dendritic cell maturation, and enhances CD8+ T‐cell activation, offering a ...
Banghua Zhong, Yijie Zhang, Honghu Wang, Lili Guo   +3 more
wiley   +1 more source

Ice recrystallization inhibitors enable efficient cryopreservation of induced pluripotent stem cells: A functional and transcriptomic analysis

Stem Cell Research
The successful use of human induced pluripotent stem cells (iPSCs) for research or clinical applications requires the development of robust, efficient, and reproducible cryopreservation protocols.
Kathleen Mommaerts, Satoshi Okawa, Margaux Schmitt, Olga Kofanova, Tracey R. Turner, Robert N. Ben, Antonio Del Sol, William Mathieson, Jens C. Schwamborn, Jason P. Acker, Fay Betsou   +10 more
doaj   +1 more source

Development and standardization of a protocol for sperm cryopreservation of two important commercial oyster species [PDF]

, 2015
Dissertação de mestrado, Aquacultura e Pescas, Faculdade de Ciências e Tecnologia, Universidade do Algarve, 2015Aquaculture activities have a huge contribution for the world food production and their development is extremely necessary to answer to the ...
Melo, Francisca Félix de Azeredo Pinto e
core