Results 111 to 120 of about 63,786 (247)

Multiple cryopreservation–warming cycles, coupled with blastocyst biopsy, negatively affect IVF outcomes [PDF]

open access: green, 2020
Ashley Aluko   +6 more
openalex   +1 more source

Mechanosensitive Cell‐Laden Shape‐Memory Scaffolds Engineered via Cryogelation

open access: yesSmall Structures, EarlyView.
GelMA‐based shape‐memory scaffolds encapsulating human adipose‐derived stem cells are fabricated via cryogelation, showing rapid recovery and high cell viability. Under cyclic compression, they promoted mechanotransduction gene expression, and composite formulations (collagen/GelMA, dECM/GelMA) retained robust shape‐memory, highlighting their promise ...
JaeYoon Lee   +4 more
wiley   +1 more source

Multifunctional tumor vaccines carrying thalidomide regulate T cell exhaustion and ferroptosis for immunotherapy strategies

open access: yesVIEW, EarlyView.
MTV can greatly achieved antigen presenting cell (APCs), and THA will be released from the polyplex core and enhanced antigen presenting, thereby prompting APC maturation and antigen presenting. The membrane antigens on MTV are degraded into small peptides by proteasomes and presented by MHC complexes.
Anmin Huang   +9 more
wiley   +1 more source

Integrated multi‐biofluid extracellular vesicle isolation with dual‐platform mass spectrometry metabolomics for prostate cancer detection

open access: yesVIEW, EarlyView.
Abstract Prostate cancer poses a significant clinical challenge due to limited screening methods and incomplete understanding of its metabolic rewiring. Extracellular vesicles (EVs) carry bioactive metabolites that mirror tumor biology, enabling mechanistic study and biomarker discovery.
Chengbang Wang   +11 more
wiley   +1 more source

A new strategy and system for the ex vivo ovary perfusion and cryopreservation: An innovation

open access: yesInternational Journal of Reproductive BioMedicine, 2017
Children and young adults, who suffer from cancer, receive gonadotoxic therapy, which destroys their fertile abilities after survival. Ovarian cryopreservation and transplantation provide the promising solution to this problem, where the ovary can be ...
Mohamed Sheata Ali Mohamed
doaj  

Considerations of Fertility in Elite Sportswomen: A Narrative Review

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Increasingly more women are participating in professional and recreational sports. Whilst vigorous intensity physical activity is considered beneficial, evidence demonstrates higher rates of menstrual disturbance in elite athletes. There is less clear evidence on the impact of elite‐level exercise on fertility outcomes.
Ariadne L'Heveder   +11 more
wiley   +1 more source

Spatial Transcriptomic Characteristics of the Aging Human Ovary

open access: yesAging Cell, EarlyView.
Troughing constructing a comprehensive spatiotemporal aging atlas on young and aged human ovaries, we revealed distinct cell types, cellular interactions, and aging‐associated gene expression changes due to aging. Specially, we detected an increase in DLK1:NOTCH3 expression which may contribute to the dysregulation of ovarian functions.
Meiling Zhang   +14 more
wiley   +1 more source

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