Crystallization and preliminary X-ray analysis of the sporulation factor SpoIIAA in its native and phosphorylated forms [PDF]
Sporulation in Bacillus begins with an asymmetric cell division producing two progeny with identical chromosomes but different developmental fates. As such, it is a simple example of cellular differentiation.
Brannigan, J A +3 more
core +1 more source
Cryopreservation of red blood cells (RBCs) is fundamentally important to modern transfusion medicine. Currently, organic solvent glycerol is utilized as the state-of-the-art cryoprotectant (CPA) for RBC cryopreservation. However, glycerol must be removed
Xiaojie Sui +8 more
semanticscholar +1 more source
Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen +30 more
wiley +1 more source
Development and standardization of a protocol for sperm cryopreservation of two important commercial oyster species [PDF]
Dissertação de mestrado, Aquacultura e Pescas, Faculdade de Ciências e Tecnologia, Universidade do Algarve, 2015Aquaculture activities have a huge contribution for the world food production and their development is extremely necessary to answer to the ...
Melo, Francisca Félix de Azeredo Pinto e
core
Preliminary X-ray diffraction analysis of YqjH from Escherichia coli: a putative cytoplasmic ferri-siderophore reductase [PDF]
YqjH is a cytoplasmic FAD-containing protein from Escherichia coli; based on homology to ViuB of Vibrio cholerae, it potentially acts as a ferri-siderophore reductase.
Andrews, Simon C. +5 more
core +2 more sources
Facile Deep Brain Electrode Coating with MXene for Improved Electrode Performance
Facile dip‐coating of commercial carbon fiber electrodes with Ti3C2Tx MXene improves electrical conductivity, reduces impedance, and enables single‐neuron recordings in the rat hippocampus over four weeks. The coating maintains biocompatibility, minimizes inflammation, and remains MRI‐compatible.
Laura Kondrataviciute +5 more
wiley +1 more source
Freeze/thaw stress induces organelle remodeling and membrane recycling in cryopreserved human mature oocytes [PDF]
Purpose: Our aim was to evaluate the ultrastructure of human metaphase II oocytes subjected to slow freezing and fixed after thawing at different intervals during post-thaw rehydration.
Albani, E. +8 more
core +1 more source
A novel blood‐brain barrier‐penetrating terpolymer nanoparticle to deliver brain‐derived neurotrophic factor (BDNF) for the treatment of Alzheimer's disease (AD) is designed. The BDNF‐TPN significantly enhances BDNF accumulation in the brain following intravenous injection, reduces apoptosis and neuroinflammation, thus promoting neuronal survival and ...
Lily Yi Li +8 more
wiley +1 more source
Effect of Marine-Derived Ice-Binding Proteins on the Cryopreservation of Marine Microalgae
Ice-binding protein (IBPs) protect cells from cryo-injury during cryopreservation by inhibiting ice recrystallization (IR), which is a main cause of cell death.
Hak Jun Kim +4 more
doaj +1 more source
An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly [PDF]
Erythropoetin-producing hepatoma (Eph) receptors are cell-surface protein tyrosine kinases mediating cell-cell communication. Upon activation, they form signaling clusters.
A Radu Aricescu +57 more
core +1 more source

