Results 91 to 100 of about 14,383 (270)

Structure of full-length Drosophila cryptochrome [PDF]

open access: yesNature, 2011
The cryptochrome/photolyase (CRY/PL) family of photoreceptors mediates adaptive responses to ultraviolet and blue light exposure in all kingdoms of life. Whereas PLs function predominantly in DNA repair of cyclobutane pyrimidine dimers (CPDs) and 6-4 photolesions caused by ultraviolet radiation, CRYs transduce signals important for growth, development,
Zoltowski, Brian D.   +5 more
openaire   +2 more sources

Circadian light-input pathways in Drosophila

open access: yesCommunicative & Integrative Biology, 2016
Light is the most important environmental cue to entrain the circadian clock in most animals. In the fruit fly Drosophila melanogaster, the light entrainment mechanisms of the clock have been well-studied.
Taishi Yoshii   +2 more
doaj   +1 more source

UV Radiation in DNA Damage and Repair Involving DNA-Photolyases and Cryptochromes

open access: yesBiomedicines, 2021
Prolonged exposure to ultraviolet radiation on human skin can lead to mutations in DNA, photoaging, suppression of the immune system, and other damage up to skin cancer (melanoma, basal cell, and squamous cell carcinoma).
Yuliya L. Vechtomova   +3 more
doaj   +1 more source

An Automated Organotypic SCN Culture System Revealing Novel Insights into VIP Regulation of Circadian Rhythm

open access: yesAdvanced Science, EarlyView.
An Automated ex vivo culture system BaSIC, tailored for SCN slices and cell culture, which automates medium exchange and ensures a stable internal environment is developed. BaSIC enables real‐time observation of tissue/cell responses to diverse but programmed stimuli.
Kui Han   +7 more
wiley   +1 more source

Sensing Magnetic Directions in Birds: Radical Pair Processes Involving Cryptochrome

open access: yesBiosensors, 2014
Birds can use the geomagnetic field for compass orientation. Behavioral experiments, mostly with migrating passerines, revealed three characteristics of the avian magnetic compass: (1) it works spontaneously only in a narrow functional window around the ...
Roswitha Wiltschko, Wolfgang Wiltschko
doaj   +1 more source

Circadian rhythms and circadian clock gene homologs of complex alga Chromera velia

open access: yesFrontiers in Plant Science, 2023
Most organisms on Earth are affected by periodic changes in their environment. The circadian clock is an endogenous device that synchronizes behavior, physiology, or biochemical processes to an approximately 24-hour cycle, allowing organisms to ...
Jitka Richtová   +10 more
doaj   +1 more source

Orientations and water dynamics of photoinduced secondary charge-separated states for magnetoreception by cryptochrome

open access: yesCommunications Chemistry, 2021
In the biological magnetic compass, blue-light photoreceptor protein of cryptochrome is thought to conduct the sensing of the Earth’s magnetic field by photoinduced sequential long-range charge-separation (CS) through a cascade of tryptophan residues, W ...
Misato Hamada   +5 more
semanticscholar   +1 more source

A Non‐Mitophagy Activity of BNIP3L/NIX in Amygdala Glutamatergic Neurons is Essential for Contextual Fear Memory Formation

open access: yesAdvanced Science, EarlyView.
Contextual fear conditioning induces BNIP3L‐dependent mitochondrial fission in glutamatergic neurons of the BLA, independently of mitophagy. Loss of BNIP3L elevates Drp1Ser637 phosphorylation, thereby suppressing mitochondrial fission, compromising ATP production, and attenuating excitatory synaptic transmission.
Xingxian Zhang   +13 more
wiley   +1 more source

Traceless Regulation of Genetic Circuitry

open access: yesAdvanced Science, EarlyView.
Energy‐based, as opposed to molecular, control offers unprecedented improvements in key circuit parameters. This review summarizes the fundamentals of such traceless switches, categorizes them by trigger modalities, and compares and contrasts distinct advantages as well as shortcomings of each kind.
Gokberk Unal, Martin Fussenegger
wiley   +1 more source

Structure and Function of Animal Cryptochromes [PDF]

open access: yesCold Spring Harbor Symposia on Quantitative Biology, 2007
Cryptochrome (CRY) is a photolyase-like flavoprotein with no DNA-repair activity but with known or presumed blue-light receptor function. Animal CRYs have DNA-binding and autokinase activities, and their flavin cofactor is reduced by photoinduced electron transfer.
N, Oztürk   +7 more
openaire   +2 more sources

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