Results 141 to 150 of about 9,604 (179)
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Effects of curcumin on Cryptosporidium parvum in vitro
Parasitology Research, 2009Cryptosporidium parvum is a zoonotic protozoan parasite having peculiarities among the apicomplexa that could be responsible for its resistance to some drugs and disinfectants against coccidia. The awareness of Cryptosporidium as a health problem in man and animal is increasing and potent drugs are urgently needed.
M, Shahiduzzaman +4 more
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Genetic Manipulation of Cryptosporidium parvum
Cryptosporidium parvum can be reliably genetically manipulated using CRISPR/Cas9 driven homologous repair coupled to in vivo propagation in immunodeficient mice. This chapter will guide through foundational procedures for excystation, transfection, infection, collection, and purification of transgenic Cryptosporidium parvum.Sebastian, Shaw +6 more
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The unusual mitochondrial compartment of Cryptosporidium parvum
Trends in Parasitology, 2005Recent studies, including the Cryptosporidium parvum Genome Project, have provided evidence for a mitochondrial-derived compartment in this parasite. This organelle appears to lack a genome, and thus must be entirely dependent on nuclear-encoded proteins. Here, we review the evidence for such an organelle in C. parvum and its probable function.
Henriquez, F L +4 more
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The response of Cryptosporidium parvum to UV light
Trends in Parasitology, 2005Ultraviolet (UV) light is being considered as a disinfectant by the water industry because it appears to be very effective for controlling potential waterborne pathogens, including Cryptosporidium parvum. However, many organisms have mechanisms such as nucleotide excision repair and photolyase enzymes for repairing UV-induced DNA damage and regaining ...
Paul A, Rochelle +3 more
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Natural History and Biology of Cryptosporidium parvum
Advances in Parasitology, 1998The taxonomy of the genus Cryptosporidium remains ambiguous, because the current criteria for speciation are insufficient to validate the 6-8 named species. Cross-transmission experiments have shown varying and conflicting results, and the limited genetic data available do not necessarily support currently proposed species designations. The reasons for
S, Tzipori, J K, Griffiths
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An immunocompetent rat model of infection with Cryptosporidium hominis and Cryptosporidium parvum
International Journal for Parasitology, 2020A major obstacle to developing vaccines against cryptosporidiosis, a serious diarrheal disease of children in developing countries, is the lack of rodent models essential to identify and screen protective immunogens. Rodent models commonly used for drug discovery are unsuitable for vaccine development because they either are purposefully ...
Denise Ann Dayao +6 more
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Cryptosporidium Parvum Gene Discovery
1999Cryptosporidium parvum is a well-recognized cause of diarrhea in humans and animals throughout the world, and is associated with a substantial degree of morbidity and mortality in patients with acquired immunodeficiency syndrome (AIDS). At the present time, there is no effective therapy for treating or preventing infection with C. parvum.
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Cryptosporidium parvum studies with dairy products
International Journal of Food Microbiology, 1999Cryptosporidium parvum is a protozoan parasite capable of causing massive waterborne outbreaks. This study was conducted to model the transfer of C. parvum oocysts from contaminated water via food contact surfaces into yogurt and ice-cream, as well as to examine oocyst survival. Propidium iodide staining, combined with a direct immunofluorescence assay,
M Q, Deng, D O, Cliver
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Gaseous disinfection of Cryptosporidium parvum oocysts
Applied and Environmental Microbiology, 1996Purified oocysts of Cryptosporidium parvum suspended in approximately 400 microliters of phosphate-buffered saline or deionized water in microcentrifuge tubes were exposed at 21 to 23 degrees C for 24 h to a saturated atmosphere of ammonia, carbon monoxide, ethylene oxide, formaldehyde, or methyl bromide gas. Controls were exposed to air.
R, Fayer +3 more
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Cryptosporidium Parvum in Children with Diarrhea in Mexico
The American Journal of Tropical Medicine and Hygiene, 1994Using an anti-oocyst wall monoclonal antibody-based immunofluorescence assay, the presence of Cryptosporidium parvum was evaluated in children with diarrhea from rural areas (selected from a door-to-door community survey) and from urban areas (patients attending hospitals) in the State of Puebla, Mexico.
K, Miller +5 more
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