Stimulation of Eryptosis by Cryptotanshinone [PDF]
Cellular Physiology and Biochemistry, 2014 Background/Aims: Cryptotanshinone, a component of Salvia miltiorrhiza Bunge roots, may trigger suicidal death or apoptosis of tumor cells and has thus been recommended for the prevention and treatment of malignancy.
Rosi Bissinger +4 more
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Cryptotanshinone ameliorates cladribine-induced cognitive impairment in rats
Asian Pacific Journal of Tropical Biomedicine, 2023 Objective: To evaluate the neuroprotective effect of cryptotanshinone against cladribine-induced cognitive impairment in rats. Methods: Rats were administered with cladribine (1 mg/kg, p.o.) and cryptotanshinone (10 and 20 mg/kg, i.p.) for four weeks ...
Khadga Raj Aran +2 more
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Cryptotanshinone targets the bacterial membrane and inhibits methicillin-resistant Staphylococcus aureus [PDF]
AMB ExpressThe widespread emergence of methicillin-resistant Staphylococcus aureus (MRSA) has become a major public health concern worldwide, highlighting the urgent need for innovative antimicrobial agents with specific efficacy against MRSA.
Qingyu Liu +9 more
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Cryptotanshinone inhibits TNF-α-induced early atherogenic events in vitro [PDF]
The Journal of Physiological Sciences, 2016 Endothelial dysfunction has been implicated in the pathogenesis of atherosclerosis. Salvia miltiorrhiza (danshen) is a traditional Chinese medicine that has been effectively used to treat cardiovascular disease. Cryptotanshinone (CTS), a major lipophilic
, Muhammad Nazrul Hakim +7 more
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Effects of cryptotanshinone in treatment of polycystic ovary syndrome in rats: a systematic review and meta-analysis [PDF]
Frontiers in PharmacologyBackgroundPCOS is a prevalent endocrine disorder characterized by metabolic dysfunctions, including insulin resistance and hyperandrogenism. Cryptotanshinone, a bioactive compound, has shown promise in addressing reproductive abnormalities.
Pingping Su +4 more
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The Influence of Selected Factors on the Aqueous Cryptotanshinone Solubility [PDF]
Pharmaceutics, 2021 The application of cryptotanshinone (CT), a diterpenoid obtained from the root of Salviae miltiorrhiza, is significantly hindered due to its poor aqueous solubility.
Justyna Kobryń +2 more
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Cryptotanshinone ameliorates CUS-induced depressive-like behaviors in mice [PDF]
Translational Neuroscience, 2021 Cryptotanshinone (CPT), a natural quinoid diterpene, isolated from Salvia miltiorrhiza, has shown various pharmacological properties. However, its effect on chronic unpredictable stress (CUS)-induced depression phenotypes and the underlying mechanism ...
Wang Kaixin +14 more
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Anticancer potential of Dendrocnide meyeniana through phytochemical profiling, ADMET analysis, molecular docking, and in silico cytotoxicity evaluation [PDF]
Scientific ReportsPhytochemicals are widely explored for cancer therapeutics due to their structural diversity and broad pharmacological activities. This study investigated the phytochemical composition and anticancer potential of Dendrocnide meyeniana using integrated in
Edlyn E. Pooten +5 more
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Validation of Madecassoside Synergy Significantly Enhanced Cryptotanshinone’s Therapeutic Efficacy Against Acne Vulgaris [PDF]
BioengineeringCurrent acne therapies face major limitations, including antibiotic resistance and skin irritancy. In this study, a synergistic strategy combining cryptotanshinone and madecassoside was developed through functional complementarity. Antibacterial activity
Yaling Guo +5 more
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Exploring the therapeutic potency of cryptotanshinone in cervical cancer: a multi-omics and network pharmacology approach [PDF]
Frontiers in GeneticsIntroductionCervical cancer remains a significant challenge in oncology with an escalating demand for novel therapeutic strategies that can navigate the complexities of its pathophysiology.
Zenghong Lu +6 more
doaj +2 more sources