Results 11 to 20 of about 4,552 (200)

Stimulation of Eryptosis by Cryptotanshinone [PDF]

Cellular Physiology and Biochemistry, 2014
Background/Aims: Cryptotanshinone, a component of Salvia miltiorrhiza Bunge roots, may trigger suicidal death or apoptosis of tumor cells and has thus been recommended for the prevention and treatment of malignancy.
Rosi Bissinger, Adrian Lupescu, Christine Zelenak, Kashif Jilani, Florian Lang   +4 more
doaj   +4 more sources

The Influence of Selected Factors on the Aqueous Cryptotanshinone Solubility [PDF]

Pharmaceutics, 2021
The application of cryptotanshinone (CT), a diterpenoid obtained from the root of Salviae miltiorrhiza, is significantly hindered due to its poor aqueous solubility.
Justyna Kobryń, Jowita Dałek, Witold Musiał   +2 more
doaj   +4 more sources

The influence of bile acids homeostasis by cryptotanshinone-containing herbs [PDF]

African Health Sciences, 2014
Herbs might affect the homeostasis of bile acids through influence of multiple metabolic pathways of bile acids.To investigate the inhibition of cryptotanshinone towards the glucuronidation of LCA, trying to indicate the possible influence of cryptotanshinone-containing herbs towards the homeostasis of bile acids.The LCA-3-glucuronidation and LCA-24 ...
Chengcheng, Gao, Tianheng, Ma, Liqun, Pang, Rui, Xie   +3 more
core   +9 more sources

Cryptotanshinone Reverses Corticosteroid Insensitivity by Inhibition of Phosphoinositide-3-Kinase-δ in Chronic Obstructive Pulmonary Disease

International Journal of COPD, 2023
Tao Xie,1 Rong Huang,1 Daishuo Deng,1 Peipei Tang,2 Yufeng Fu,2 Yulong Zheng,1 Yufeng Wan1 1Department of Respiratory Diseases, The Affiliated Huai’an Hospital of Xuzhou Medical University, Huai’an, Jiangsu, People’s Republic of China; 2Institute of ...
Xie T, Huang R, Deng D, Tang P, Fu Y, Zheng Y, Wan Y   +6 more
doaj   +1 more source

Exploring the therapeutic potency of cryptotanshinone in cervical cancer: a multi-omics and network pharmacology approach [PDF]

Frontiers in Genetics
IntroductionCervical cancer remains a significant challenge in oncology with an escalating demand for novel therapeutic strategies that can navigate the complexities of its pathophysiology.
Zenghong Lu, Gangfeng Zhu, Xiaofei Feng, Yi Xiang, Cixiang Chen, Huiting Yuan, Zhixing Chen   +6 more
doaj   +2 more sources

Preparation and optimization of surface stabilized cryptotanshinone nanocrystals with enhanced bioavailability

Frontiers in Pharmacology, 2023
Cryptotanshinone (CTS) is a plant product extracted from Salvia miltiorrhiza Bunge with various pharmacological significances. In addition to its activities against coronary heart disease, hyperlipidemia, stroke, hepatitis and chronic renal failure, it ...
Wenzheng Zhao, Wenzheng Zhao, Wenzheng Zhao, Bohao Ruan, Bohao Ruan, Xiaoyi Sun, Zhenwei Yu, Zhenwei Yu   +7 more
doaj   +3 more sources

Validation of Madecassoside Synergy Significantly Enhanced Cryptotanshinone’s Therapeutic Efficacy Against Acne Vulgaris

Bioengineering
Current acne therapies face major limitations, including antibiotic resistance and skin irritancy. In this study, a synergistic strategy combining cryptotanshinone and madecassoside was developed through functional complementarity. Antibacterial activity
Yaling Guo, Xiaobin Yang, Lifeng Tang, Tao Liang, Rongshen Xiao, Qiang Liu   +5 more
doaj   +2 more sources

Uncovering the Mechanisms of Cryptotanshinone as a Therapeutic Agent Against Hepatocellular Carcinoma [PDF]

Frontiers in Pharmacology, 2020
Hepatocellular carcinoma (HCC) is a fatal and dominant form of liver cancer that currently has no effective treatment or positive prognosis. In this study, we explored the antitumor effects of cryptotanshinone (CPT) against HCC and the molecular ...
Yi Luo, Yi Luo, Lei Song, Lei Song, Xinyu Wang, Yujie Huang, Yujie Huang, Yongqiang Liu, Yongqiang Liu, Qi Wang, Qi Wang, Ming Hong, Ming Hong, Zhongyu Yuan   +13 more
doaj   +3 more sources

Cryptotanshinone Protects Against Acute Pulmonary Edema

Experimed, 2023
Objective: Cryptotanshinone (CTS) is a compound with anti-inflammatory, anti-bacterial, anti-oxidative and anti-aggregant functions. We aimed to determine the effects of CTS on α-naphtilthiourea (ANTU)-induced acute pulmonary edema.Materials and Methods: In this study, 4 groups (control, sham, ANTU and ANTU+CTS) were established from a total of 40 rats.
YILMAZ, Ümit, DEMİR, Mehmet
openaire   +3 more sources

Cryptotanshinone induces cell cycle arrest and apoptosis through the JAK2/STAT3 and PI3K/Akt/NFkB pathways in cholangiocarcinoma cells

Drug Design, Development and Therapy, 2017
Fayong Ke,1,2,* Zheng Wang,1,2,* Xiaoling Song,1,2 Qiang Ma,1,2 Yunping Hu,2 Lin Jiang,2 Yijian Zhang,2 Yingbin Liu,1,2 Yong Zhang,1 Wei Gong1,2 1Department of General Surgery, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai,
Ke FY, Wang Z, Song XL, Ma Q, Hu YP, Jiang L, Zhang YJ, Liu YB, Zhang Y, Gong W   +9 more
doaj   +1 more source