Results 11 to 20 of about 5,330 (211)

Cryptotanshinone ameliorates cladribine-induced cognitive impairment in rats

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2023
Objective: To evaluate the neuroprotective effect of cryptotanshinone against cladribine-induced cognitive impairment in rats. Methods: Rats were administered with cladribine (1 mg/kg, p.o.) and cryptotanshinone (10 and 20 mg/kg, i.p.) for four weeks ...
Khadga Raj Aran   +2 more
doaj   +2 more sources

Stimulation of Eryptosis by Cryptotanshinone [PDF]

open access: yesCellular Physiology and Biochemistry, 2014
Background/Aims: Cryptotanshinone, a component of Salvia miltiorrhiza Bunge roots, may trigger suicidal death or apoptosis of tumor cells and has thus been recommended for the prevention and treatment of malignancy.
Rosi Bissinger   +4 more
doaj   +3 more sources

The Influence of Selected Factors on the Aqueous Cryptotanshinone Solubility [PDF]

open access: yesPharmaceutics, 2021
The application of cryptotanshinone (CT), a diterpenoid obtained from the root of Salviae miltiorrhiza, is significantly hindered due to its poor aqueous solubility.
Justyna Kobryń   +2 more
doaj   +3 more sources

Cryptotanshinone inhibits TNF-α-induced early atherogenic events in vitro [PDF]

open access: yesThe Journal of Physiological Sciences, 2016
Endothelial dysfunction has been implicated in the pathogenesis of atherosclerosis. Salvia miltiorrhiza (danshen) is a traditional Chinese medicine that has been effectively used to treat cardiovascular disease. Cryptotanshinone (CTS), a major lipophilic
, Muhammad Nazrul Hakim   +7 more
core   +3 more sources

Preparation and optimization of surface stabilized cryptotanshinone nanocrystals with enhanced bioavailability

open access: yesFrontiers in Pharmacology, 2023
Cryptotanshinone (CTS) is a plant product extracted from Salvia miltiorrhiza Bunge with various pharmacological significances. In addition to its activities against coronary heart disease, hyperlipidemia, stroke, hepatitis and chronic renal failure, it ...
Wenzheng Zhao   +7 more
doaj   +3 more sources

Cryptotanshinone ameliorates CUS-induced depressive-like behaviors in mice [PDF]

open access: yesTranslational Neuroscience, 2021
Cryptotanshinone (CPT), a natural quinoid diterpene, isolated from Salvia miltiorrhiza, has shown various pharmacological properties. However, its effect on chronic unpredictable stress (CUS)-induced depression phenotypes and the underlying mechanism ...
Wang Kaixin   +14 more
doaj   +3 more sources

Cryptotanshinone attenuates in vitro oxLDL-induced pre-lesional atherosclerotic events. [PDF]

open access: yesPlanta Medica, 2011
Development of early stage atherosclerosis involves the activation of endothelial cells by oxidized low-density lipoprotein (oxLDL) with subsequent increases in endothelial permeability and expression of adhesion molecules favoring the adherence of ...
Abd. Kadir, Arifah   +7 more
core   +3 more sources

Cryptotanshinone-Induced Permeabilization of Model Phospholipid Membranes: A Biophysical Study

open access: yesMembranes
The Danshen terpenoid cryptotanshinone (CPT) is gaining enormous interest in light of its various outstanding biological activities. Among those, CPT has been shown to interact with cell membranes and, for instance, to have antibacterial activity ...
Julia Ortiz   +3 more
doaj   +3 more sources

Effect of Co-Solvents, Modified Starch and Physical Parameters on the Solubility and Release Rate of Cryptotanshinone from Alcohologels [PDF]

open access: yesMolecules
(1) Background: The aim of the work was to investigate the influence of selected physico-chemical factors on the solubility and release rate of CT (cryptotanshinone) in alcohologels.
Justyna Kobryń   +4 more
doaj   +2 more sources

Cryptotanshinone Protects Against Acute Pulmonary Edema

open access: yesExperimed, 2023
Objective: Cryptotanshinone (CTS) is a compound with anti-inflammatory, anti-bacterial, anti-oxidative and anti-aggregant functions. We aimed to determine the effects of CTS on α-naphtilthiourea (ANTU)-induced acute pulmonary edema.Materials and Methods: In this study, 4 groups (control, sham, ANTU and ANTU+CTS) were established from a total of 40 rats.
YILMAZ, Ümit, DEMİR, Mehmet
openaire   +2 more sources

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