Results 21 to 30 of about 5,330 (211)

Cryptotanshinone From Inhibits the Growth of Tumors and Enhances the Efficacy of Chemotherapy in a Gastric Cancer Mouse Model

open access: yesNatural Product Communications, 2022
Cryptotanshinone is a quinone diterpene extracted from the traditional Chinese medicine Salvia miltiorrhiza root that shows obvious anticancer activity.
Wenkai Wu   +8 more
doaj   +1 more source

Comparative Proteomics Analysis Reveals the Reversal Effect of Cryptotanshinone on Gefitinib-Resistant Cells in Epidermal Growth Factor Receptor-Mutant Lung Cancer

open access: yesFrontiers in Pharmacology, 2022
Cryptotanshinone (CTS) is a lipophilic constituent of Salvia miltiorrhiza, with a broad-spectrum anticancer activity. We have observed that CTS enhances the efficacy of gefitinib in human lung cancer H1975 cells, yet little is known about its molecular ...
Peiheng Cai   +6 more
doaj   +1 more source

Targeting oncogenic mutations in colorectal cancer using cryptotanshinone

open access: yesPLOS ONE, 2020
Colorectal cancer (CRC) is one of the most prevalent types of cancer in the world and ranks second in cancer deaths in the US. Despite the recent improvements in screening and treatment, the number of deaths associated with CRC is still very significant.
Haswanth Vundavilli   +5 more
openaire   +4 more sources

Nitrogen Fertilization Improves Growth and Bioactive Compound Content for Salvia miltiorrhiza Bunge

open access: yesHorticulturae, 2023
Salvia miltiorrhiza B., an herb used in traditional Chinese medicine, has been widely used to prevent and treat cardiovascular and other diseases. Currently, the majority of medicinal plants used in the US are imported from foreign countries, which ...
Zhiheng Xing   +4 more
doaj   +1 more source

Cryptotanshinone protects against adriamycin-induced mitochondrial dysfunction in cardiomyocytes [PDF]

open access: yesPharmaceutical Biology, 2015
The serious side effect of Adriamycin (ADR) is cardiomyopathy. Cryptotanshinone (CRY) is widely and safely used as antioxidant with MTD more than 5 mg/g in rats (p.o).The objective of this study is to study the protection effects of CRY against ADR-induced mitochondrial dysfunction in cardiomyocytes.The chemical administration lasted for 20 days with ...
Yanshan, Zhang   +6 more
openaire   +2 more sources

Cryptotanshinone Inhibits the Growth of HCT116 Colorectal Cancer Cells Through Endoplasmic Reticulum Stress-Mediated Autophagy

open access: yesFrontiers in Pharmacology, 2021
Among cancers, colorectal cancer (CRC) has one of the highest annual incidence and death rates. Considering severe adverse reactions associated with classical chemotherapy medications, traditional Chinese medicines have become potential drug candidates ...
Xiaojing Fu   +5 more
doaj   +1 more source

Plant Growth and the Contents of Major Bioactive Compounds of Salvia miltiorrhiza Bunge Grown in Mississippi, United States

open access: yesHorticulturae, 2023
Salvia miltiorrhiza Bunge (danshen) is a traditional herbal medicine and has been widely used to prevent and treat cardiovascular and other diseases. Currently, the majority of medicinal plants, including danshen, used in the United States are imported ...
Zhiheng Xing   +4 more
doaj   +1 more source

Endophyte Chaetomium globosum D38 Promotes Bioactive Constituents Accumulation and Root Production in Salvia miltiorrhiza [PDF]

open access: yes, 2018
Salvia miltiorrhiza is known for tanshinones and salvianolic acids, which have been shown to have a protective effect against ROS, especially for cardiovascular diseases and other various ailments of human organs.
Han, T   +9 more
core   +3 more sources

Pharmacokinetics and tissue distribution of bleomycin-induced idiopathic pulmonary fibrosis rats treated with cryptotanshinone

open access: yesFrontiers in Pharmacology, 2023
Introduction: Cryptotanshinone(CTS), a compound derived from the root of Salvia miltiorrhiza, has been linked to various of diseases, particularly pulmonary fibrosis.
Xiangjun He   +6 more
doaj   +1 more source

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