Results 41 to 50 of about 4,552 (200)

Novel perspectives on the therapeutic role of cryptotanshinone in the management of stem cell behaviors for high-incidence diseases

Frontiers in Pharmacology, 2022
Cryptotanshinone (CTS), a diterpenoid quinone, is found mostly in Salvia miltiorrhiza Bunge (S. miltiorrhiza) and plays a crucial role in many cellular processes, such as cell proliferation/self-renewal, differentiation and apoptosis.
Xiaomeng Guo, Ruishuang Ma, Meng Wang, Benson Wui-Man Lau, Xiaopeng Chen, Yue Li   +5 more
doaj   +1 more source

Cryptotanshinone Attenuates Oxygen-Glucose Deprivation/ Recovery-Induced Injury in an in vitro Model of Neurovascular Unit

Frontiers in Neurology, 2019
Cryptotanshinone (CTs), an active component isolated from the root of Salvia miltiorrhiza (SM), has been shown to exert potent neuroprotective property.
Hongye Zhao, Hongye Zhao, Tiezheng Zheng, Xiaohan Yang, Ming Fan, Lingling Zhu, Shuhong Liu, Liying Wu, Changkai Sun, Changkai Sun   +9 more
doaj   +1 more source

Synergistic Effects of Cryptotanshinone and Senkyunolide I in Guanxinning Tablet Against Endogenous Thrombus Formation in Zebrafish

Frontiers in Pharmacology, 2021
Thrombosis is a key pathological event in cardiovascular diseases, and is also the most important targeting process for their clinical management. New drug development in thrombosis treatment is still in great demand. According to the traditional Chinese
Jun Li, Hao Liu, Zhenzhong Yang, Qingqing Yu, Lu Zhao, Yi Wang, Yi Wang   +6 more
doaj   +1 more source

Cryptotanshinone Ameliorates Radiation-Induced Lung Injury in Rats

Evidence-Based Complementary and Alternative Medicine, 2019
Cryptotanshinone (CTS) was reported to repress a variety of systemic inflammation and alleviate cardiac fibrosis, but it is still unclear whether CTS could prevent radiation-induced lung injury (RILI). Here, we investigated the effects and underlying mechanisms of CTS on a RILI rat model.
Yifang Jiang, Fengming You, Jie Zhu, Chuan Zheng, Ran Yan, Jinhao Zeng   +5 more
openaire   +2 more sources

Inhibitory effects of tanshinones towards the catalytic activity of UDP-glucuronosyltransferases (UGTs)

Pharmaceutical Biology, 2017
Contents: Danshen is a popular herb employed to treat cardiovascular and cerebrovascular diseases worldwide. Danshen–drug interaction has not been well studied.
Xu-Xin Zhang, Yun-Feng Cao, Li-Xuan Wang, Xiao-Lin Yuan, Zhong-Ze Fang   +4 more
doaj   +1 more source

Machine Learning Accelerates Crystallization for Structure Determination

Angewandte Chemie, Volume 138, Issue 25, 15 June 2026.
Single‐crystal X‐ray diffraction (SCXRD) is often constrained by the difficulty of obtaining suitable crystals. Here, a machine learning‐accelerated co‐crystal discovery workflow is established for a crystalline mate strategy that achieves over 95% prediction accuracy and experimentally delivers 114 co‐crystals from 120 candidates.
Cui‐Zhou Luan, Xue‐Zhi Wang, Jian‐Guo Song, Yu Gu, Jing Wu, Ye‐Ting Wang, Jin‐Feng Liang, Jia‐Le Rao, Mo Xie, Jonathan R. Nitschke, Dan Li   +10 more
wiley   +2 more sources

Effect of Ellagic Acid and Cryptotanshinone on Cell Viability/Cytotoxicity, Metastasis, and Oxidative Stress in Triple-Negative Breast Cancer Cells

Experimed
Objective: Triple-negative breast cancer (TNBC) has the highest rate of metastases and relapses as well as the worst overall survival of all breast cancers.
Ümit Yılmaz, Mehmet Fatih Seyhan
doaj   +1 more source

Quantitative Determination and Validation of Four Ketones in Salvia miltiorrhiza Bunge Using Quantitative Proton Nuclear Magnetic Resonance Spectroscopy

Molecules, 2020
Salvia mltiorrhiza Bunge (SMB) is native to China, whose dried root has been used as medicine. A few chromatographic- or spectrometric-based methods have already been used to analyze the lipid-soluble components in SMB.
Yuanyuan Li, Zhuoni Hou, Feng Su, Jipeng Chen, Xiaodan Zhang, Ling Xu, Dongfeng Yang, Zongsuo Liang   +7 more
doaj   +1 more source

Images of cryptotanshinone loaded ethosomes.

, 2016
Images of cryptotanshinone loaded ethosomes.
Ke Ma (260231), Zhenwei Yu (3148452), Gang Han (127634), Hongyan Lv (3148455)   +3 more
core   +1 more source

An in-silico study examining the induction of apoptosis by Cryptotanshinone in metastatic melanoma cell lines

BMC Cancer, 2018
Background Metastatic melanoma is an aggressive form of skin cancer that evades various anti-cancer treatments including surgery, radio-,immuno- and chemo-therapy.
Radhika S. Saraf, Aniruddha Datta, Chao Sima, Jianping Hua, Rosana Lopes, Michael Bittner   +5 more
doaj   +1 more source