Results 91 to 100 of about 5,245 (194)
ABSTRACT Salvia miltiorrhiza produces pharmacologically bioactive diterpenoid tanshinones which are regulated by jasmonate (JA) and abscisic acid (ABA) signalling, while their crosstalk in this process remains unclear. Here, we demonstrated that MeJA and ABA acted synergistically to enhance tanshinone biosynthesis.
Tingyao Liu +8 more
wiley +1 more source
Ovarian cancer is the most malignant gynecologic cancer among women worldwide. Cryptotanshinone (CT), isolated from Salvia miltiorrhiza Bunge, has been identified as a potential therapeutic agent in treating several malignant tumors, but the molecular ...
Yufei Yang +6 more
doaj +1 more source
Advances in Inhaled Nanoparticle Drug Delivery for Pulmonary Disease Management
Pulmonary disorders remain a global health challenge. This review explores critical innovations in inhaled nanoparticle drug delivery systems focusing on their potential to revolutionize treatment strategies for a wide spectrum of pulmonary diseases. We highlight recent breakthroughs in carrier materials, performance evaluations in vitro and in vivo ...
Yunzhou Fan +3 more
wiley +1 more source
Cryptotanshinone inhibits breast cancer cell growth by suppressing estrogen receptor signaling [PDF]
Estrogen receptor (ER) is a major therapeutic target for the treatment of breast cancer, because of the crucial role of estrogen signaling deregulation in the development and progression of breast cancer. In this study, we report the identification of a novel ERα binding compound, cryptotanshinone (CPT), by screening the CADD database.
Shanhu, Li +8 more
openaire +2 more sources
Research advancements and evaluation of multifactor‐induced murine models for gastric cancer
Murine models for gastric cancer. Abstract As one of the most prevalent gastrointestinal malignancies in humans, gastric cancer (GC) is often detected at an advanced stage, resulting in a poor prognosis and ranking it the fifth leading cause of cancer‐related deaths.
Yiqing Wang +5 more
wiley +1 more source
Heat dissipation by magnetic nanoparticles (MNPs) under an alternating magnetic field can be used to selectively treat cancer tissues. Antibodies conjugated to MNPs can enhance the therapeutic effects of hyperthermia by altering antibody-antigen ...
Satoshi Ota +4 more
doaj +1 more source
Medicinal Plants for the Treatment of Hypertrophic Scars [PDF]
Hypertrophic scar is a complication of wound healing and has a high recurrence rate which can lead to significant abnormity in aesthetics and functions. To date, no ideal treatment method has been established.
Chen, J-Y +5 more
core +1 more source
Emerging glycolysis targeting and drug discovery from chinese medicine in cancer therapy [PDF]
Molecular-targeted therapy has been developed for cancer chemoprevention and treatment. Cancer cells have different metabolic properties from normal cells.
Chen, J, Shen, J, Wang, N, Wang, Z
core +1 more source
Targeting gut microbiota and metabolites in cancer radiotherapy
Radiotherapy (RT) efficacy and toxicity are influenced by gut microbiota and their metabolites. This review explores how probiotics, prebiotics, and microbial byproducts (e.g., short‐chain fatty acids [SCFAs]) mitigate radiation damage and enhance tumour radiosensitivity.
Shuling Ma +6 more
wiley +1 more source
Current Status of Herbal Medicines in Chronic Liver Disease Therapy: The Biological Effects, Molecular Targets and Future Prospects [PDF]
Chronic liver dysfunction or injury is a serious health problem worldwide. Chronic liver disease involves a wide range of liver pathologies that include fatty liver, hepatitis, fibrosis, cirrhosis, and hepatocellular carcinoma.
Feng, Y +5 more
core +2 more sources

