Cryptotanshinone attenuates in vitro oxLDL-induced pre-lesional atherosclerotic events. [PDF]
Planta Medica, 2011 Development of early stage atherosclerosis involves the activation of endothelial cells by oxidized low-density lipoprotein (oxLDL) with subsequent increases in endothelial permeability and expression of adhesion molecules favoring the adherence of ...
Abd. Kadir, Arifah +7 more
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Frontiers in Pharmacology, 2023 Cryptotanshinone (CTS) is a plant product extracted from Salvia miltiorrhiza Bunge with various pharmacological significances. In addition to its activities against coronary heart disease, hyperlipidemia, stroke, hepatitis and chronic renal failure, it ...
Wenzheng Zhao +7 more
doaj +3 more sources
The influence of bile acids homeostasis by cryptotanshinone-containing herbs [PDF]
African Health Sciences, 2014 Background: Herbs might affect the homeostasis of bile acids through influence of multiple metabolic pathways of bile acids. Aim: The present study aims to investigate the inhibition of cryptotanshinone towards the glucuronidation of LCA, trying to ...
Gao, Chengcheng +3 more
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Integrating Network Pharmacology and Metabolomics to Elucidate the Mechanism of Cryptotanshinone Against Platelet Aggregation [PDF]
Current Issues in Molecular BiologyCryptotanshinone (CTS), an antiplatelet compound from Salvia miltiorrhiza, exhibits in vitro potency comparable to aspirin. This study integrated network pharmacology and metabolomics to elucidate its underlying mechanisms.
Jielan Huang +13 more
doaj +2 more sources
Blood biochemical landscape and new insights into clinical decision-making for polycystic ovary syndrome in Chinese women: a prospective cohort study [PDF]
Frontiers in EndocrinologyIntroductionThe Polycystic ovary syndrome (PCOS), a prevalent endocrine disorder affecting women’s reproductive and metabolic health, faces diagnostic challenges due to heterogeneous clinical presentations and the absence of reliable biomarkers.
Yutong Li +7 more
doaj +2 more sources
Cryptotanshinone Suppresses BVDV Propagation by Suppressing Cell Apoptosis and Restoring Hormone Secretion in Bovine Granulosa Cells [PDF]
VirusesBovine viral diarrhea virus (BVDV) constitutes a significant pathogen adversely threatening reproductive performance in the cattle industry, primarily by inducing ovarian dysfunction characterized by aberrant hormone synthesis and impaired follicular ...
Xiaoliang Chen +11 more
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Cryptotanshinone-Induced Permeabilization of Model Phospholipid Membranes: A Biophysical Study
MembranesThe Danshen terpenoid cryptotanshinone (CPT) is gaining enormous interest in light of its various outstanding biological activities. Among those, CPT has been shown to interact with cell membranes and, for instance, to have antibacterial activity ...
Julia Ortiz +3 more
doaj +3 more sources
Effect of Co-Solvents, Modified Starch and Physical Parameters on the Solubility and Release Rate of Cryptotanshinone from Alcohologels [PDF]
Molecules(1) Background: The aim of the work was to investigate the influence of selected physico-chemical factors on the solubility and release rate of CT (cryptotanshinone) in alcohologels.
Justyna Kobryń +4 more
doaj +2 more sources
Cryptotanshinone Protects Against Acute Pulmonary Edema
Experimed, 2023 Objective: Cryptotanshinone (CTS) is a compound with anti-inflammatory, anti-bacterial, anti-oxidative and anti-aggregant functions. We aimed to determine the effects of CTS on α-naphtilthiourea (ANTU)-induced acute pulmonary edema.Materials and Methods: In this study, 4 groups (control, sham, ANTU and ANTU+CTS) were established from a total of 40 rats.
YILMAZ, Ümit, DEMİR, Mehmet
openaire +2 more sources
Frontiers in Pharmacology, 2022 Cryptotanshinone (CTS) is a lipophilic constituent of Salvia miltiorrhiza, with a broad-spectrum anticancer activity. We have observed that CTS enhances the efficacy of gefitinib in human lung cancer H1975 cells, yet little is known about its molecular ...
Peiheng Cai +6 more
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