Results 101 to 110 of about 10,077,982 (396)
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Propagation of Light in Photonic Crystal Fibre Devices
, 2005 We describe a semi-analytical approach for three-dimensional analysis of photonic crystal fibre devices. The approach relies on modal transmission-line theory. We offer two examples illustrating the utilization of this approach in photonic crystal fibres:
Akbari M +18 more
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Returning to the Classroom [PDF]
, 2012 Two students return to college to complete their degrees, while balancing families and professional ...
Galarza, Crystal, \u2713
core +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Electron‐Lattice Synergistic Coordination for Boosting the Electro‐Optic Response of the Crystal
Advanced ScienceThe electro‐optic (E‐O) response is fundamental where the refractive index of materials can be modulated by the external electric field. Up to now, E‐O modulation has become a critical technology in photonics, quantum optics, modern communication, etc ...
Jinfeng Han +7 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Advanced SciencePhotoelectric conversion in ferroelectric crystals can support many important applications in modern on‐chip technology, but suffering from two problems, low responsive current and narrow responsive range.
Yaqian Wang +6 more
doaj +1 more source
Crystals, 2019 Single crystal fibers of 30% Er3+-doped compound of Y3(ScxGa1−x)5O12 have been grown by using the micro-pulling down (μ-PD) technique successfully.
Zhijiang Che +6 more
doaj +1 more source
Design and Focused Ion Beam Fabrication of Single Crystal Diamond Nanobeam Cavities
, 2010 We present the design and fabrication of nanobeam photonic crystal cavities in single crystal diamond for applications in cavity quantum electrodynamics.
Babinec, T. M. +4 more
core +1 more source