Results 81 to 90 of about 42,358 (203)

ZDHHC18‐Mediated Palmitoylation of ORF3a Promotes SARS‐CoV‐2 Pathogenesis by Antagonizing TRIM16‐Mediated Ubiquitination and Proteasomal Degradation

Advanced Science, Volume 13, Issue 43, 3 August 2026.
Palmitoylation by ZDHHC18 blocks ORF3a K27‐linked ubiquitination mediated by TRIM16, thereby preventing its proteasomal degradation and strengthening viral pathogenesis. Targeting palmitoylation through a pharmacological inhibitor (2‐BP), a competitive inhibitory peptide (OPIP), or adenovirus‐mediated knockdown of ZDHHC18 expression presents a ...
Sidi Yang, Kun Li, Lihong Liu, Linsen Zeng, Qifeng Deng, Jiacheng Huang, Xiaoran Dong, Xin Wang, Jianwei Liang, Hongchao Liu, Hong Peng, Yuxin Lin, Xiaolu Xie, Yuzhen Ye, Tiefeng Xu, Zhaohuan Wang, Chun‐Mei Li, Deyin Guo   +17 more
wiley   +1 more source

Compressive Sensing Convolution Improves Long Short-Term Memory for Ocean Wave Spatiotemporal Prediction

Journal of Marine Science and Engineering
This study proposes a Compressive Sensing Convolutional Long Short-Term Memory (CSCL) model that aims to improve short-term (12–24 h) forecast accuracy compared to standard ConvLSTM.
Lingxiao Zhao, Yijia Kuang, Junsheng Zhang, Bin Teng   +3 more
doaj   +1 more source

Ni–Cr Substitution in TiFe: An Integrated Experimental–Modeling Study of Phase Stability and Hydride Thermodynamics

Advanced Energy and Sustainability Research, Volume 7, Issue 8, August 2026.
Combined experimental and theoretical approaches reveal how Cr and Ni substitution in TiFe‐based alloys tune lattice expansion and hydride thermodynamics. While both elements increase hydride stability, they exert opposite effects on the entropy of hydrogen desorption, providing new insight into thermodynamic design of AB‐type hydrogen storage ...
Evans Pericoli, Viola Ferretti, Ebert Alvares, Paul Jerabek, Claudio Pistidda, Luca Pasquini   +5 more
wiley   +1 more source

How Generative AI Affects Team Communication in Secondary Education: A Qualitative Investigation

Journal of Computer Assisted Learning, Volume 42, Issue 4, August 2026.
ABSTRACT Background The integration of Generative AI (GenAI) into collaborative learning in secondary education has created new possibilities for this pedagogical approach. It has also raised concerns about its impact on team communication, particularly, for adolescent learners whose collaborative competencies are still developing.
Wenjie Hu, Cecilia Ka Yuk Chan
wiley   +1 more source

Adenovirus Vector‐Mediated In Vivo Knock‐in Treatment of Neonatal Phenylketonuria Mice Using Terminally Cleaved Donor DNA

The Journal of Gene Medicine, Volume 28, Issue 8, August 2026.
We successfully developed a highly efficient knock‐in adenovirus vector, AxPah‐6g‐cut. This vector cleaves not only the genomic target site but also the terminus of the donor DNA in the vector. When this vector was intravenously administered twice to phenylketonuria (Pahenu2) mice together with a Cas9‐expressing vector, AxCBCas9, it resulted in the ...
Megumi Yamaji, Hirotaka Tabata, Mariko Nakamura, Ryoko Fuse, Tadashi Okada, Shun‐Ichi Ohba, Tomokazu Ohishi, Manabu Kawada, Izumu Saito, Shigeto Sato, Tomoko Nakanishi   +10 more
wiley   +1 more source

Metal Halide Perovskite Quantum Dots for Luminescence Sensing and Imaging

Nano Select, Volume 7, Issue 8, August 2026.
This review highlights recent advances in metal halide perovskite quantum dots (PQDs)‐based photoluminescence, chemiluminescence, and electroluminescence sensing methods, as well as bioimaging applications. Key challenges, potential solutions, and future opportunities are discussed to guide the development of robust PQD‐based sensing platforms ...
Tooba Hallaj, Rana Salari, Seyyed Morteza Seyyed Alavi, Muhammad Munir, Niko Hildebrandt, Mohammad Amjadi   +5 more
wiley   +1 more source

Evolutionarily conserved hydrophobicity and sterics in TM3/TM4 balance Orai1 pore opening

Protein Science, Volume 35, Issue 8, August 2026.
Abstract The calcium (Ca2+) channel Orai1—the pore‐forming subunit of the Ca2+ release‐activated Ca2+ channel—is opened by its physiological activator, the endoplasmic reticulum (ER)‐resident Ca2+ sensor stromal interaction molecule 1 (STIM1) upon ER Ca2+ store‐depletion.
Maximilian Fröhlich, Tamara Radišković, Valentina Hopl, Magdalena Prantl, Hadil Najjar, Selina Harant, Diana Thallinger, Muhammad Shehzad Anwar, Ferdinand Horvath, Julia Söllner, Yuliia Nazarenko, Matthias Sallinger, Nora Müller, Adéla Tiffner, Sarah Weiß, Herwig Grabmayr, Heinrich Krobath, Isabella Derler   +17 more
wiley   +1 more source

TEORIAS EDUCACIONAIS SUBSIDIADORAS E SUBSIDIÁRIAS AO COMPUTER SUPPORTED COLLABORATIVE LEARNING

Revista da Fundarte
O presente artigo visa identificar como a teoria da aprendizagem colaborativa apoiada por computador (CSCL) é fundamentada pela teoria construtivista de Jean Piaget e sócio-construtivista de Lev Vygotsky, além de sua relação com outras contribuições ...
Luís Antônio Licks Missel Machado, Fabrício Soares, Miriam dos Santos Nunes, Patrícia Fernanda da Silva, Liane Margarida Rockenbach Tarouco   +4 more
doaj   +1 more source

Salt forms of the monoazo dye Mordant Orange 1

Acta Crystallographica Section C, Volume 82, Issue 8, Page 427-436, August 2026.
The crystal structures of eight salt forms of the carboxylate‐functionalized monoazo dye Mordant Orange 1 are presented and discussed, primarily in terms of their coordination behaviour.The crystal structures of eight salt forms of the carboxylate‐functionalized monoazo dye Mordant Orange 1 are presented and discussed, primarily in terms of their ...
Alan R. Kennedy, Connor MacCall, Michael W. Reid, Ben Shaw, Maxwell Taylor   +4 more
wiley   +1 more source

Matching Software and Context in Open Learning Scenarios - The Use of Log File Analysis to Evaluate Didactical Fit

E-learning and Education, 2005
We describe the use of log file analysis to investigate whether the use of CSCL applications corresponds to its didactical purposes. Exemplarily we examine the use of the web-based system CommSy as software support for project-oriented university courses.
Bernd Pape, Monique Janneck, Martin Klein   +2 more
doaj