Results 11 to 20 of about 9,582 (257)
Dual NDP52 Function in Persistent CSFV Infection [PDF]
Frontiers in Microbiology, 2020 Viruses have evolved many mechanisms to escape host antiviral responses. Previously, we found that classical swine fever virus (CSFV) infection induces autophagy using the autophagosome as a self-replication site, thereby evading the host immune response
Shuangqi Fan +13 more
doaj +4 more sources
A Triple Gene-Deleted Pseudorabies Virus-Vectored Subunit PCV2b and CSFV Vaccine Protects Pigs against PCV2b Challenge and Induces Serum Neutralizing Antibody Response against CSFV [PDF]
Vaccines, 2022 Porcine circovirus type 2 (PCV2) is endemic worldwide. PCV2 causes immunosuppressive infection. Co-infection of pigs with other swine viruses, such as pseudorabies virus (PRV) and classical swine fever virus (CSFV), have fatal outcomes, causing the swine
Selvaraj Pavulraj +7 more
semanticscholar +6 more sources
LDHA-lactate axis modulates mitophagy inhibiting CSFV replication. [PDF]
J VirolABSTRACT Lactate dehydrogenase A (LDHA) plays a crucial role in regulating lactate synthesis in various biological processes. Lactate, a byproduct of glycometabolism, has been recognized as a unique molecule with implications in both metabolism and immunity.
Zeng S +11 more
europepmc +4 more sources
Characterization of a Cytopathogenic Reporter CSFV [PDF]
Viruses, 2021 Cytopathogenic (cp) pestiviruses frequently emerge in cattle that are persistently infected with the bovine viral diarrhea virus (BVDV) as a consequence of RNA recombination and mutation.
Carina M Reuscher +3 more
semanticscholar +5 more sources
Transcriptome analysis of PK-15 cells expressing CSFV NS4A [PDF]
BMC Veterinary Research, 2022 Background Classical swine fever (CSF) is a severe disease of pigs that results in huge economic losses worldwide and is caused by classical swine fever virus (CSFV).
Huifang Lv +6 more
semanticscholar +5 more sources
Self-Assembling Nanovaccine Enhances Protective Efficacy Against CSFV in Pigs [PDF]
Frontiers in Immunology, 2021 Classical swine fever virus (CSFV) is a highly contagious pathogen, which pose continuous threat to the swine industry. Though most attenuated vaccines are effective, they fail to serologically distinguish between infected and vaccinated animals ...
Zehui Liu +7 more
semanticscholar +5 more sources
Cholesterol Biosynthesis Modulates CSFV Replication
Viruses, 2022 Classical swine fever (CSF) caused by the classical swine fever virus (CSFV) has resulted in severe losses to the pig industry worldwide. It has been proposed that lipid synthesis is essential for viral replication, and lipids are involved in viral ...
Xiaodong Zou +8 more
semanticscholar +4 more sources
Induction of autophagy and suppression of type I IFN secretion by CSFV [PDF]
Autophagy, 2020 Macroautophagy/autophagy plays an essential role in cellular responses to pathogens. However, the precise mechanisms and signaling pathways that modulate cellular autophagy in classical swine fever virus (CSFV)-infected host cells have not been confirmed.
Baoming Xie +8 more
semanticscholar +5 more sources
Antiviral Research, 2023 Pseudorabies (PR) and classical swine fever (CSF) are economically important infectious diseases of pigs. Most pig farms in China are immunized against these two diseases. Here, we describe a stabilized E2 protein as an immunogen inserted into the PRV genome as a bivalent live virus-vectored vaccine.
Yang-yang Sun +12 more
semanticscholar +3 more sources
LDHB inhibition induces mitophagy and facilitates the progression of CSFV infection [PDF]
Autophagy, 2020 Cellular metabolism caters to the energy and metabolite needs of cells. Although the role of the terminal metabolic enzyme LDHB (lactate dehydrogenase B) in the glycolysis pathway has been widely studied in cancer cells, its role in viral infection is ...
Shuangqi Fan +9 more
semanticscholar +3 more sources