Results 101 to 110 of about 3,671 (212)

Expression of mutant TIE2 p.L914F during mouse development causes embryonic lethality and defects in vascular remodeling

Developmental Dynamics, EarlyView.
Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff, Sandra Schrenk, Kara Soroko, Chhiring Sherpa, Ashok Arasu, Damien Reynaud, Elisa Boscolo   +6 more
wiley   +1 more source

Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle

Developmental Dynamics, EarlyView.
Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell, Tracy Eng, Jeffrey D. Amack, David Pruyne   +3 more
wiley   +1 more source

Evaluating the Impact of a Patient Navigation Program on Treatment Timeliness, Continuity, and Follow-Up Outcomes for Patients With Digestive Tract Cancer at Kenyatta Hospital

JCO Global Oncology
PURPOSEGI cancers contribute substantially to cancer-related morbidity and mortality in Kenya, where patients often present with advanced disease and experience delayed treatment, interruptions, and loss to follow-up.
Wilson Kiprop Likhubi, Catherine Naliaka Nyongesa, Felix Kilumbi Kisienya   +2 more
doaj   +1 more source

CTC-GMM: CTC Guided Modality Matching For Fast and Accurate Streaming Speech Translation

2024 IEEE Spoken Language Technology Workshop (SLT)
Models for streaming speech translation (ST) can achieve high accuracy and low latency if they're developed with vast amounts of paired audio in the source language and written text in the target language. Yet, these text labels for the target language are often pseudo labels due to the prohibitive cost of manual ST data labeling.
Rui Zhao 0017, Jinyu Li 0001, Ruchao Fan, Matt Post   +3 more
openaire   +2 more sources

Carbon‐Negative Upcycling of Sewage Sludge into Superiorly Stable Gel Via Liquid‐Phase Utilization Strategy for Water‐Remediation

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This work developed a low‐temperature sludge hydrothermal coupled with gel crosslinking strategy which could upgrade the waste liquid generated from sewage sludge hydrothermal treatment into the hydrothermal‐liquid‐gel. The inventive hydrothermal‐liquid‐gel exhibited the enhanced pollutant removal capability, high synthetic stability, and superior ...
Zifan Liu, Sunxinyi Wang, Lingxiao Lu, Weiguo Zhang, Qiang Zheng, Cailiang Yue, Huimin Chang, Xiaohui Lu, Ming Xu, Zhi Qian, Qing Zhou, Fuqiang Liu, Baoshan Xing   +12 more
wiley   +1 more source

Transendocardial injection of expanded autologous CD34+ cells after myocardial infarction: Design of the EXCELLENT trial

ESC Heart Failure, Volume 12, Issue 2, Page 1455-1463, April 2025.
Abstract Aims The extent of irreversible cardiomyocyte necrosis after acute myocardial infarction (AMI) is a major determinant of residual left ventricular (LV) function and clinical outcome. Cell therapy based on CD34+ cells has emerged as an option to help repair the myocardium and to improve outcomes.
Jerome Roncalli, François Roubille, Nicolas Meyer, Giulio Pompilio, Lionel Leroux, Philippe Henon, Guillaume Trebuchet, Anthony Criquet, Matthieu de Kalbermatten, Eric Saloux, Alain Manrique, Pierre‐Yves Marie, Deepak L. Bhatt, Scott D. Solomon, Gilles Montalescot, David E. Newby, Faiez Zannad, on behalf of the EXCELLENT Trial Investigators   +17 more
wiley   +1 more source

Aromaticity in Octahedral Cyclopentadienylberyllium Transition Metal Clusters

European Journal of Inorganic Chemistry, EarlyView.
Density functional theory studies on (CpBe)6M (M = Mn to Cu) complexes related to the experimentally known (CpBe)6Ni predict octahedral or distorted octahedral structures. The CpBe ligands are weak‐field ligands stabilizing high formal transition metal oxidation states by pπ → dπ forward electron donation to the central transition metal. (CpBe)6Ni is a
Huidong Li, Jinfeng Luo, Haoyu Chen, Qunchao Fan, Zhixiang Fan, Gregory H. Robinson, R. Bruce King, Henry F. Schaefer III   +7 more
wiley   +1 more source

A case study for emergency management and urban resilience under seismic risks. Part III: an integrated digital platform for Digital Inspection and Monitoring Assistant (DIMA)

Emergency Management Science and Technology
The current paper presents a digital platform developed to manage the damage evaluation campaign for buildings in the aftermath of earthquakes, or any event such as industrial explosions or fires, landslides, floods, or tsunamis.
Ahmed Mebarki, Boumediène Oukaci, Khaled Meziani, Nabila Tahrat, Lakhdar Becheikh, Ali Brahimi, Amar Zekri, Nabila Houmer, Chahinez Alliche, Hadjer Boumeshad, Tarek Khiri, Younès Marouf, Hani Mebtouche, Houssem Ghiat, Sofiane Merrad   +14 more
doaj   +1 more source

Chiral HPLC Separation of Phosphonothrixin and Phosphonate Derivatives and Electronic Circular Dichroism Characterization of the Isolated Enantiomers

ELECTROPHORESIS, EarlyView.
Natural compound phosphonothrixin's herbicidal activity resides exclusively in its (S)‐enantiomer, yet existing enantioselective syntheses are cumbersome, and direct chiral LC separation is hampered by the compound's high polarity, lack of aromatic groups, and metal chelation–induced peak tailing.
Mirna Maalouf, Maximilian Knab, Leon Gessner, Marc Engelhardt, Stella Friedrich, Harald Gross, Frank Boeckler, Chambers C. Hughes, Michael Lämmerhofer   +8 more
wiley   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source