Results 81 to 90 of about 127,497 (313)
Using CTCs for pharmacogenomic analysis
Pharmacological Research, 2016 In the era of precision medicine in oncology, pharmacogenomic assessment is a vital step in delivering personalized care. Increasing evidence points towards the importance of assessing molecular features of the advanced disease, rather than relying on the primary tumor sample, in order to appreciate the evolution of the tumor and to target relevant ...
Christopher D, Hart +5 more
openaire +2 more sources
, 2020 Supplemental material, sj-jpg-2-ctc-10.1177_2515256420926354 for Nucleus–Plasma Membrane Contact Sites Are Formed During Spermiogenesis in the Acoel Symsagittifera roscoffensis by Matthew J. Hayes, Anne-C. Zakrzewski, Timothy P.
Matthew J. Hayes (7201070) +3 more
core +1 more source
, 2023 Supplemental material, sj-xlsx-11-ctc-10.1177_25152564231211976 for Phylogenetic and Structural Analyses of VPS13 Proteins in Archaeplastida Reveal Their Complex Evolutionary History in Viridiplantae by Sébastien Leterme, Olivier Bastien, Riccardo Aiese ...
Olivier Bastien (7815) +4 more
core +1 more source
Advanced Materials Technologies, EarlyView.A label‐free impedimetric biosensor based on electroactive 3D porous graphene foam enables ultrasensitive and selective detection of CD81 protein and MCF‐7 cell‐derived extracellular vesicles in human serum. Detection limits of 0.048 fg/mL for CD81 and ∼24 EVs/mL are achieved, demonstrating a robust platform for selective, label‐free, and ...
Michael Robert Furness +11 more
wiley +1 more source
, 2023 Supplemental material, sj-pptx-1-ctc-10.1177_25152564231211976 for Phylogenetic and Structural Analyses of VPS13 Proteins in Archaeplastida Reveal Their Complex Evolutionary History in Viridiplantae by Sébastien Leterme, Olivier Bastien, Riccardo Aiese ...
Olivier Bastien (7815) +4 more
core +1 more source
Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq
Advanced Science, EarlyView.Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su +10 more
wiley +1 more source
Redirecting a Native Ene‐Reductase Toward Desaturation With Reverse Enantioselectivity
Angewandte Chemie, EarlyView.A native ene‐reductase, XenA, was repurposed to catalyze the reverse‐enantioselective desaturation of cyclohexanones. The final variant was obtained through extensive protein engineering, combining PROSS‐guided computational design with mutagenesis and screening.
Qing‐Qing Zeng +4 more
wiley +2 more sources
, 2023 Supplemental material, sj-pdb-7-ctc-10.1177_25152564231211976 for Phylogenetic and Structural Analyses of VPS13 Proteins in Archaeplastida Reveal Their Complex Evolutionary History in Viridiplantae by Sébastien Leterme, Olivier Bastien, Riccardo Aiese ...
Olivier Bastien (7815) +4 more
core +1 more source
Adipocyte‐Derived Leptolin Enhances Energy Expenditure and Prevents Obesity
Advanced Science, EarlyView.We identified a novel adipokine, which we named leptolin. In humans, leptolin levels in white adipose tissue were positively correlated with exercise and negatively associated with body mass index. We observed elevated leptolin in serum from athletes and lower leptolin in serum from obese individuals.
Jiarui Liu +17 more
wiley +1 more source
Deep Learning-Based 3D Reconstruction for Defect Detection in Shipbuilding Sub-Assemblies
SensorsOvershooting defects in shipbuilding subassemblies are essential to ensure the final product’s overall integrity and safety. In this work, we focus on the automatic detection of overshooting defects in simple and T-shaped sub-assemblies by employing ...
Paula Arcano-Bea +5 more
doaj +1 more source