Results 171 to 180 of about 3,671 (212)

The Imbalance Between Tumor Immunosurveillance and Tumor Immune Escape in Glioblastoma

Immunology &Cell Biology, EarlyView.
(Left)The identification and elimination of tumour cells is enabled by the infiltration of functional innate and adaptive immune effectors into the TME, such as natural killer cells (NK cells) and cytotoxic T cells (CD8 T cells). Effective innate and adaptive immune responses facilitate immunological control of malignant outgrowth.
Sarah J. MacDonald, Matthew Drill, Padmakrishnan C. Jayakrishnan, Richard P. Sequeira, Terence J. O'Brien, Rosalind L. Jeffree, Mastura Monif   +6 more
wiley   +1 more source

Dental Caries in Permanent Molars of Children Previously Treated With Silver Fluoride Gel/Sodium Fluoride Varnish in Their Primary Dentition: A Retrospective Cohort Study

International Journal of Paediatric Dentistry, EarlyView.
ABSTRACT Introduction Children with more caries in the primary dentition have been observed to have greater caries risk in the permanent dentition. In a previous trial, we determined lesion arrest in primary teeth, where 38% SDF gel and 2.5% NaF varnish were applied sequentially.
Tania Carola Padilla Cáceres, Jorge Luis Castillo, Claudia Mariela Vera Reyes, Marilynn Rothen, Lloyd L. Mancl, Peter Milgrom   +5 more
wiley   +1 more source

Magnetic Particles for CTC Enrichment [PDF]

Cancers, 2020
Here, we review the characteristics and synthesis of magnetic nanoparticles (MNPs) and place these in the context of their usage in the immunomagnetic enrichment of Circulating Tumor Cells (CTCs). The importance of the different characteristics is explained, the need for a very specific enrichment is emphasized and different (commercial) magnetic ...
Leon Terstappen, Pascal Jonkheijm, Michiel Stevens   +2 more
exaly   +4 more sources

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Models to study CTCs and CTC culture methods

2023
The vast majority of cancer-related deaths are due to the presence of disseminated disease. Understanding the metastatic process is key to achieving a reduction in cancer mortality. Particularly, there is a need to understand the molecular mechanisms that drive cancer metastasis, which will allow the identification of curative treatments for metastatic
Cristóbal, Fernández-Santiago, Rafael, López-López, Roberto, Piñeiro   +2 more
openaire   +2 more sources

CTC-Derived Models: A Window into the Seeding Capacity of Circulating Tumor Cells (CTCs)

Cells, 2019
Metastasis is the main cause of cancer-related death owing to the blood-borne dissemination of circulating tumor cells (CTCs) early in the process. A rare fraction of CTCs harboring a stem cell profile and tumor initiation capacities is thought to possess the clonogenic potential to seed new lesions. The highest plasticity has been generally attributed
Patrycja Pawlikowska, Françoise Farace, Vincent Faugeroux   +2 more
exaly   +4 more sources

Longitudinally collected CTCs and CTC-clusters and clinical outcomes of metastatic breast cancer

Breast Cancer Research and Treatment, 2016
Circulating tumor cell (CTC) is a well-established prognosis predictor for metastatic breast cancer (MBC), and CTC-cluster exhibits significantly higher metastasis-promoting capability than individual CTCs. Because measurement of CTCs and CTC-clusters at a single time point may underestimate their prognostic values, we aimed to analyze longitudinally ...
Hushan Yang, Zhaomei Mu, Chun Wang
exaly   +3 more sources

CTCs in Metastatic Breast Cancer

2012
Circulating tumor cells (CTCs), enumerated by the Food and Drugs Administration-cleared CellSearch(®) system, are an independent prognostic factor of progression-free survival (PFS) and overall survival (OS) in metastatic breast cancer (MBC) patients.
Giordano A., Cristofanilli M.
openaire   +3 more sources

Quantum CTC's in General Relativity

General Relativity and Gravitation, 2001
Closed timelike curves and their importance in theories of quantum gravity are discussed at the example of tunneling spacetimes constructed from generalized Misner spacetimes. These models are quantum mechanically stable and show negative energy densities and closed timelike curves at the Planck scale.
Garay, Luis J., González-Díaz, Pedro F.   +1 more
openaire   +2 more sources

Methodology for the Isolation and Analysis of CTCs

2020
The majority of deaths related to breast cancer are caused by metastasis. Understanding the process of metastasis is key to achieve a reduction on breast cancer mortality. Currently, liquid biopsies are gaining attention in this regard. Circulating tumor cells (CTCs), an important component of liquid biopsies, are cells shed from primary tumor that ...
Clotilde, Costa, Ana B, Dávila-Ibáñez
openaire   +2 more sources

Portrait of a polyp: the CTC dilemma

Abdominal Imaging, 2008
N ...
Franco Iafrate, Cesare Hassan, Perry J. Pickhardt, Alessandro Pichi, STAGNITTI, ANDREA, Angelo Zullo, DI GIULIO, Emilio, LAGHI, ANDREA   +7 more
openaire   +2 more sources