Results 41 to 50 of about 11,409 (260)

Melanoma and Pancreatic CTCs Captured on Filters.

, 2013
CTCs were enriched from blood samples from another melanoma patient and from a patient with pancreatic cancer using OncoQuick, CTCs from the enriched fraction were captured on filters, and cells were cultured as described.
Susan D. Patrick (315237), Arthur Berg (128764), Ping Xin (124291), Paul J. Mosca (315248), Siyang Zheng (315241), Gary A. Clawson (315235), Eric Kimchi (315236), Ramdane Harouaka (315239), Todd Schell (315245), Rogerio I. Neves (315247), Diane Thiboutot (315249), Kevin F. Staveley-O’Carroll (315246)   +11 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Hierarchical Multitask Learning With CTC [PDF]

2018 IEEE Spoken Language Technology Workshop (SLT), 2018
In Automatic Speech Recognition, it is still challenging to learn useful intermediate representations when using high-level (or abstract) target units such as words. For that reason, when only a few hundreds of hours of training data are available, character or phoneme-based systems tend to outperform word-based systems.
Ramon Sanabria, Florian Metze
openaire   +2 more sources

Evaluating metastatic risk in breast cancer through CTCs and L1CAM expression [PDF]

IntroductionCirculating tumor cells (CTCs) and L1 cell adhesion molecule (L1CAM) are associated with breast cancer (BC) metastasis. This study investigated their potential as predictive biomarkers for lymph node metastasis in early-stage invasive breast ...
Yan Huang, Qianhui Ouyang, Qiong Guo, Zhouxi Chen, Ni Liao, Jiansheng Yi, Yi Hu, Jingjing Chen, Wei Zhou, Chen Zeng, Fulan Tan   +10 more
core   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Optimization Scheme for Effective Track Length at Suburban Railway Stations Based on CTCS Standard

Chengshi guidao jiaotong yanjiu
Objective Through optimized design, the effective track length at suburban railway stations is shortened, achieving the goal of reducing the station yard scale, downsizing land occupation, and lowering construction costs.
Liang ZHAO
doaj   +1 more source

Clinical Significance of TWIST-Positive Circulating Tumor Cells in Patients with Esophageal Squamous Cell Carcinoma

Gut and Liver, 2021
Background/Aims: Unlike other gastrointestinal tract cancers, there are relatively few reports on the clinical significance of circulating tumor cells (CTCs) and TWIST, a marker of epithelial-mesenchymal transition, in patients with esophageal squamous ...
Hyun Jung Lee, Gwang Ha Kim, Su Jin Park, Chae Hwa Kwon, Moon Won Lee, Bong Eun Lee, Dong Hoon Baek, Hoseok I   +7 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Cell-surface vimentin–positive macrophage-like circulating tumor cells as a novel biomarker of metastatic gastrointestinal stromal tumors

OncoImmunology, 2018
The clinical utility of circulating tumor cells (CTCs) has been investigated in numerous publications, but CTCs that express very typical immune cell markers have not been reported.
Heming Li, Qing H. Meng, Hyangsoon Noh, Neeta Somaiah, Keila E. Torres, Xueqing Xia, Izhar S. Batth, Cissimol P. Joseph, Mengyuan Liu, Ruoyu Wang, Shulin Li   +10 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source