Clinical correlates of blood-derived circulating tumor DNA in pancreatic cancer [PDF]
Journal of Hematology & Oncology, 2019 Background Treatment outcomes for patients with advanced pancreatic ductal adenocarcinoma (PDAC) remain dismal. There are unmet needs for understanding the biologic basis of this malignancy using novel next-generation sequencing technologies.
Hitendra Patel +7 more
doaj +3 more sources
The prognostic and clinical utility of circulating tumor DNA in diffuse large B-cell lymphoma: a systematic review and meta-analysis [PDF]
npj Precision OncologyCirculating tumor DNA (ctDNA) provides a minimally invasive tool for assessing tumor burden and genetic evolution in diffuse large B-cell lymphoma (DLBCL).
Shayan Forghani +12 more
doaj +2 more sources
Circulating Tumor DNA (ctDNA) in Kidney Cancer: A Narrative Review
Société Internationale d’Urologie Journal, 2023 Circulating tumor DNA (ctDNA) has been investigated as a potential noninvasive biomarker for disease prognostication, monitoring, and treatment selection in various tumor types, including renal cell carcinoma (RCC). In this narrative review,
Wesley Yip, A. Ari Hakimi
doaj +1 more source
Identification of Genetic Alterations by Circulating Tumor DNA in Leiomyosarcoma: A Molecular Analysis of 73 Patients [PDF]
Journal of Immunotherapy and Precision Oncology, 2020 Background: Leiomyosarcoma is a malignant mesenchymal tumor of cells of smooth muscle lineage arising commonly in retroperitoneum, uterus, large veins, and the limbs.
Junaid Arshad +5 more
doaj +1 more source
Liquid biopsy in CNS tumors: Current status & future perspectives
Indian Journal of Pathology and Microbiology, 2022 Precise classification of central nervous system (CNS) malignancies is vital for the treatment and prognostication. Identification of noninvasive markers can be of importance to guide treatment decisions and in monitoring treatment response.
Nuzhat Husain +3 more
doaj +1 more source
Fragmentomic cfDNA Patterns in Noninvasive Prenatal Testing and Beyond
Journal of Biomedicine and Translational Research, 2021 The release of fetoplacental cell-free DNA (cfDNA) into the maternal bloodstream opened up new avenues towards noninvasive prenatal testing (NIPT) for aneuploidies, hereditary DNA mutations and other pregnancy-related developmental disorders ...
Kavish Kohabir +2 more
doaj +1 more source
ctDNA as a prognostic biomarker in resectable CLM: Systematic review and meta-analysis
Open Life Sciences, 2023 Cell-free circulating tumor DNA (ctDNA) is synthesized by tumor cells, including metastatic tumors, and circulates in the bloodstream. Evidence suggests that ctDNA is a potential predictive and prognostic biomarker for colorectal cancer (CRC), but its ...
Wang Da +10 more
doaj +1 more source
Description of the calf thymus DNA-malathion complex behavior by multi-spectroscopic and molecular modeling techniques: EMF at low and high frequency approaches [PDF]
Iranian Journal of Basic Medical Sciences, 2021 Objective(s): Small molecules can bind to DNA via covalent or non-covalent interactions, which results in altering or inhibiting the function of DNA. Thus, understanding the interaction patterns of medicines or other small molecules can be very crucial ...
Tahmineh Sohrabi +5 more
doaj +1 more source
Société Internationale d’Urologie Journal, 2023 None.
Manishkumar S. Patel, Liang Wang
doaj +1 more source
ctDNA as a novel and promising approach for cancer diagnosis
EXCLI Journal : Experimental and Clinical Sciences, 2023 Hepatocellular carcinoma (HCC) is one of the most prevalent forms of cancer worldwide. Therefore, it is essential to diagnose and treat HCC patients promptly.
Negin Biglari +4 more
doaj +1 more source