Results 21 to 30 of about 29,283 (270)

Fragmentomic cfDNA Patterns in Noninvasive Prenatal Testing and Beyond

open access: yesJournal of Biomedicine and Translational Research, 2021
The release of fetoplacental cell-free DNA (cfDNA) into the maternal bloodstream opened up new avenues towards noninvasive prenatal testing (NIPT) for aneuploidies, hereditary DNA mutations and other pregnancy-related developmental disorders ...
Kavish Kohabir   +2 more
doaj   +1 more source

Identification of Genetic Alterations by Circulating Tumor DNA in Leiomyosarcoma: A Molecular Analysis of 73 Patients [PDF]

open access: yesJournal of Immunotherapy and Precision Oncology, 2020
Background: Leiomyosarcoma is a malignant mesenchymal tumor of cells of smooth muscle lineage arising commonly in retroperitoneum, uterus, large veins, and the limbs.
Junaid Arshad   +5 more
doaj   +1 more source

Benefits of Plasma Over Other Body Fluids for Circulating Tumor DNA Detection in Genitourinary Tumors

open access: yesSociété Internationale d’Urologie Journal, 2023
None.
Manishkumar S. Patel, Liang Wang
doaj   +1 more source

ctDNA as a novel and promising approach for cancer diagnosis

open access: yesEXCLI Journal : Experimental and Clinical Sciences, 2023
Hepatocellular carcinoma (HCC) is one of the most prevalent forms of cancer worldwide. Therefore, it is essential to diagnose and treat HCC patients promptly.
Negin Biglari   +4 more
doaj   +1 more source

ctDNA as a prognostic biomarker in resectable CLM: Systematic review and meta-analysis

open access: yesOpen Life Sciences, 2023
Cell-free circulating tumor DNA (ctDNA) is synthesized by tumor cells, including metastatic tumors, and circulates in the bloodstream. Evidence suggests that ctDNA is a potential predictive and prognostic biomarker for colorectal cancer (CRC), but its ...
Wang Da   +10 more
doaj   +1 more source

Description of the calf thymus DNA-malathion complex behavior by multi-spectroscopic and molecular modeling techniques: EMF at low and high frequency approaches [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2021
Objective(s): Small molecules can bind to DNA via covalent or non-covalent interactions, which results in altering or inhibiting the function of DNA. Thus, understanding the interaction patterns of medicines or other small molecules can be very crucial ...
Tahmineh Sohrabi   +5 more
doaj   +1 more source

ctDNA-guided adjuvant treatment after radical-intent treatment of metastatic spread from colorectal cancer—the first interim results from the OPTIMISE study

open access: yes, 2023
Patients with detectable ctDNA after radical-intent treatment of metastatic spread from colorectal cancer (mCRC) have a very high risk of recurrence, which may be prevented with intensified adjuvant chemotherapy (aCTh).
Torben Frøstrup Hansen (12987262)   +10 more
core   +1 more source

Application Value of ctDNA-based MRD Dedection 
in Early Stage Non-small Cell Lung Cancer after Radical Surgery

open access: yesChinese Journal of Lung Cancer, 2021
Lung cancer is the most common malignant tumor in the world, among which non-small cell lung cancer (NSCLC) accounts for about 85% of the total number of lung cancers.
Shihua DOU, Hongsheng XIE, Lin YANG
doaj   +1 more source

Identification of germline cancer predisposition variants during clinical ctDNA testing [PDF]

open access: yes, 2021
Next-generation sequencing of circulating tumor DNA (ctDNA) is a non-invasive method to guide therapy selection for cancer patients. ctDNA variant allele frequency (VAF) is commonly reported and may aid in discerning whether a variant is germline or ...
Bryan P. Schneider   +11 more
core   +1 more source

Circulating biomarkers in malignant pleural mesothelioma

open access: yesExploration of Targeted Anti-tumor Therapy, 2020
Malignant pleural mesothelioma (MPM) is an aggressive tumor strictly connected to asbestos exposure. Prognosis is dismal as diagnosis commonly occurs in advanced stage.
Giuseppe Viscardi   +6 more
doaj   +1 more source

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