Results 101 to 110 of about 28,326 (256)
Journal of Surgical Oncology, EarlyView.ABSTRACT Background and Objectives To evaluate the prognostic significance of baseline and longitudinal changes in prognostic nutritional index (PNI) in localized pancreatic ductal adenocarcinoma (PDAC) and to assess the complementary prognostic value of PNI with tumor burden measured by circulating tumor DNA (ctDNA).
Alex Horowitz +9 more
wiley +1 more source
BMC Cancer, 2018 Background Circulating tumour DNA (ctDNA) may serve as a measure of tumour burden and a useful tool for non-invasive monitoring of cancer. However, ctDNA is not always detectable in patients at time of diagnosis of metastatic disease. Therefore, there is
Ashleigh C. McEvoy +10 more
doaj +1 more source
Journal of Surgical Oncology, EarlyView.ABSTRACT Background and Objectives Colorectal cancer (CRC) has been on the rise in adults younger than 50. Surgical resection is a potentially curative treatment option for patients with colorectal liver metastases (CRLM). The aim of this study was to describe patient and tumor characteristics associated with disease‐specific survival in young patients
Gabrielle Grob +6 more
wiley +1 more source
Challenges in Using ctDNA to Achieve Early Detection of Cancer
, 2017 Early detection of cancer is a significant unmet clinical need. Improved technical ability to detect circulating tumor-derived DNA (ctDNA) in the cell-free DNA (cfDNA) component of blood plasma via next-generation sequencing and established correlations ...
Olivier Elemento, Imran S Haque
core +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Response to neoadjuvant chemoradiotherapy (NACRT) in locally advanced colorectal cancer (CRC) varies widely, and accurately identifying poor responders is crucial for guiding timely treatment modification. This study aimed to develop an integrated predictive model combining radiomics derived from routine radiotherapy non‐contrast planning ...
Sin‐Hua Moi +6 more
wiley +1 more source
, 2017 Samuel J Klempner,1,2 Pareen Mehta,3 Alexa B Schrock,4 Siraj M Ali,4 Sai-Hong Ignatius Ou5 1The Angeles Clinic and Research Institute, Los Angeles, CA, USA; 2Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA;
Schrock AB +4 more
core
Novel imaging and circulating biomarkers in hepatic malignancies
, 2020 Colorectal cancer (CRC) that has metastasised to the liver has a median survival of less than 24 months unless patients have resectable disease. Liver-directed therapies target disease to improve hepatic disease-control.
Winter, Helen
core +1 more source
Nanopore Sequencing for HPV in Oropharyngeal Squamous Cell Carcinoma and Benign Tonsil Specimens
Otolaryngology–Head and Neck Surgery, EarlyView.Abstract Objectives Human papillomavirus (HPV) accounts for the majority of oropharyngeal squamous cell carcinoma (OPSCC) cases in the United States but understanding the prevalence of high‐risk HPV in oropharyngeal tissue remains poor. We evaluated nanopore sequencing, a novel rapid, and long‐read sequencing platform, on OPSCC tissue and tested it in ...
Mikayla G. Hubbard +5 more
wiley +1 more source
Clinical characteristics associated with ctDNA concentration.
, 2016 Correlation between T0 ctDNA concentration tertiles and (A) tumor burden defined by the sum of the RECIST target lesions (Mann-Whitney test) and (B) presence of liver metastasis (Fisher’s exact test).
Eleonora Zonta (3153192) +11 more
core +1 more source
Precision Medical Sciences, EarlyView.Breast cancer subtypes, estrogen receptor‐positive (ER+), HER2‐enriched, and TNBC, are defined by genomic and epigenetic signatures. Multi‐omics profiling, immunotherapy, liquid biopsy, and AI‐driven radiogenomics enable precision medicine. Tools like Oncotype DX and PAM50 support personalized care.
Samina Malik +4 more
wiley +1 more source