Results 141 to 150 of about 47,434 (363)

Application of liquid biopsy in lung cancer management

open access: yesIndian Journal of Pathology and Microbiology
Current advances in the understanding of the lung cancer landscape have drastically changed the approach to treating a patient with lung carcinoma. The field has progressed from analyzing single gene to using advanced techniques like next-generation ...
Shraddhanjali Satapathy   +2 more
doaj   +1 more source

Intra-Tumor Heterogeneity of Colorectal Cancer Necessitates the Multi-Regional Sequencing for Comprehensive Mutational Profiling

open access: yesCancer Management and Research, 2021
Shaohua Guo,1,2,* Yumeng Ye,3,* Xinyi Liu,4 Yuan Gong,5 Mingyan Xu,4 Lele Song,4,6 Hongyi Liu1 1Department of General Surgery, The First Medical Center of the Chinese PLA General Hospital, Beijing, People’s Republic of China; 2Department of ...
Guo S   +6 more
doaj  

A New Method for the Determination of Nucleic Acid Using an Eu3+– nicotinic Acid Complex as a Resonance Light Scattering Probe [PDF]

open access: yes, 2008
This study found that in Tris-HCl buffer, the resonance light scattering (RLS) intensity of the Eu3+-nicotinic acid system can be greatly enhanced by nucleic acids and the enhanced intensity is proportional to the concentration of nucleic acid in the ...
Collins   +10 more
core   +2 more sources

Rapid detection and quantification of ultralow‐concentration nanoparticles based on nanopore array blockage

open access: yesDroplet, EarlyView.
We developed a nanopore array strategy based on nanoparticle blockage for rapid detection and quantification of ultralow‐concentration nanoparticles. Using hydraulic force, nanoparticles are driven through an array of pores smaller than the nanoparticles, and optical microscopy tracks blockage progression to obtain quantitative concentration ...
Rami Yazbeck   +6 more
wiley   +1 more source

Liquid Biopsies in Head and Neck Cancers: Recent Developments Across Biofluids, Analytes, and Molecular Features

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Head and neck cancers (HNCs) are too often diagnosed at advanced stages when outcomes are poor. Additionally, robust tools for the early detection of recurrence remain elusive. These gaps drive interest in so‐called liquid biopsy approaches for HNC detection, prognostication, and surveillance.
Patricia J. Brooks, Scott V. Bratman
wiley   +1 more source

Randomized study of FOLFIRI plus either panitumumab or bevacizumab for wild-type KRAS colorectal cancer-WJOG 6210G [PDF]

open access: yes, 2016
This randomized phase II trial compared panitumumab plus fluorouracil, leucovorin, and irinotecan (FOLFIRI) with bevacizumab plus FOLFIRI as second-line chemotherapy for wild-type (WT) KRAS exon 2 metastatic colorectal cancer (mCRC) and to explore the ...
Boku Narikazu   +17 more
core   +1 more source

Merkel Cell Carcinoma: Evolving Therapeutics, Continued Challenges

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Merkel Cell Carcinoma (MCC) is a rare, aggressive neuroendocrine malignancy with rising incidence, influenced by ultraviolet (UV) radiation and Merkel cell polyomavirus (MCPyV). Methods This review summarizes recent advances in MCC management, based on an analysis of current literature, focusing on immune checkpoint inhibitors (ICIs)
Hunter A. Holley   +6 more
wiley   +1 more source

Molecular Profiling of Hepatocellular Carcinoma Using Circulating Cell-Free DNA. [PDF]

open access: yes, 2019
PurposeMolecular profiling has been used to select patients for targeted therapy and determine prognosis. Noninvasive strategies are critical to hepatocellular carcinoma (HCC) given the challenge of obtaining liver tissue biopsies.Experimental designWe ...
Abdel-Wahab, Reham   +27 more
core   +1 more source

Detection of Hypomethylation in Long-ctDNA

open access: yesClinical Chemistry, 2022
Simon A Joosse, Klaus Pantel
openaire   +2 more sources

Diagnostic Accuracy of HPV Circulating Tumor DNA Following Non‐Diagnostic FNA of a Cystic Lateral Neck Mass

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Cystic lateral neck masses in adults commonly represent nodal metastases from HPV‐associated oropharyngeal squamous cell carcinoma (OPSCC) or benign lesions. Because cystic lesions are relatively acellular, fine‐needle aspiration (FNA) is often non‐diagnostic.
Michael R. Papazian   +4 more
wiley   +1 more source

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