Results 11 to 20 of about 39,021 (326)
Liquid Biopsy, ctDNA Diagnosis through NGS [PDF]
Life, 2021 Liquid biopsy with circulating tumor DNA (ctDNA) profiling by next-generation sequencing holds great promise to revolutionize clinical oncology. It relies on the basis that ctDNA represents the real-time status of the tumor genome which contains information of genetic alterations. Compared to tissue biopsy, liquid biopsy possesses great advantages such
Chen Lin +4 more
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Role of ctDNA in Breast Cancer [PDF]
Cancers, 2022 Breast cancer is currently classified by immunohistochemistry. However, technological advances in the detection of circulating tumor DNA (ctDNA) have made new options available for diagnosis, classification, biological knowledge, and treatment selection.
Marta Sant +3 more
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Chinese Journal of Lung Cancer, 2021 Lung cancer is the most common malignant tumor in the world, among which non-small cell lung cancer (NSCLC) accounts for about 85% of the total number of lung cancers.
Shihua DOU, Hongsheng XIE, Lin YANG
doaj +1 more source
Cancer Biology & Medicine, 2021 Objective: Apatinib is an oral TKI targeting VEGFR-2. Single-agent apatinib treatment has been shown to produce an objective response in patients with pretreated mBC. Oral vinorelbine also holds promise as a treatment of choice in patients with mBC. This
Anjie Zhu +19 more
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Cancer Biology & Medicine, 2019 As immunotherapy has gained increasing interest as a new foundation for cancer therapy, some atypical response patterns, such as pseudoprogression and hyperprogression, have garnered the attention of physicians. Pseudoprogression is a phenomenon in which
Wenxiao Jia +4 more
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Review of precision cancer medicine: Evolution of the treatment paradigm. [PDF]
, 2020 In recent years, biotechnological breakthroughs have led to identification of complex and unique biologic features associated with carcinogenesis. Tumor and cell-free DNA profiling, immune markers, and proteomic and RNA analyses are used to identify ...
Fountzilas, Elena +3 more
core +1 more source
Minimally invasive differential diagnosis of melanocytic intraocular neoplasms
Российский офтальмологический журнал, 2023 Purpose: to analyze the mutation frequency of the GNAQ/GNA11 gene in circulating tumor DNA and genotypes of the polymorphic marker C3435T of the ABCB1 gene in a large sample of patients with intraocular melanocytic neoplasms (IMN).Material and methods ...
A. Yu. Tsygankov +4 more
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Predicting lung cancer recurrence from circulating tumour DNA. Commentary on 'Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution' [PDF]
, 2017 No abstract ...
Daniel J Murphy +11 more
core +1 more source
Circulating biomarkers in malignant pleural mesothelioma
Exploration of Targeted Anti-tumor Therapy, 2020 Malignant pleural mesothelioma (MPM) is an aggressive tumor strictly connected to asbestos exposure. Prognosis is dismal as diagnosis commonly occurs in advanced stage.
Giuseppe Viscardi +6 more
doaj +1 more source
Impact of linker histone in the formation of ambochlorin-calf thymus DNA complex: Multi-spectroscopic, stopped-flow, and molecular modeling approaches [PDF]
Iranian Journal of Basic Medical Sciences, 2021 Objective(s): This study aimed to evaluate the role of the linker histone (H1) in the binding interaction between ambochlorin (Amb), and calf thymus DNA (ctDNA) as binary and ternary systems.
Azam Askari +8 more
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