Results 151 to 160 of about 119,169 (307)
iNew Medicine, EarlyView.ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu +5 more
wiley +1 more source
iNew Medicine, EarlyView.ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid +4 more
wiley +1 more source
Lack of Association between Promoter Gene Polymorphism (-318 C/T) and Multiple [PDF]
Journal of Sciences, Islamic Republic of Iran, 2008 Multiple sclerosis (MS), a chronic inflammatory demyelinating disease of the central nervous system is believed to have a T cell-mediated autoimmune etiology. The cytotoxic T lymphocyte antigen 4 (CTLA-4) gene is a strong candidate for the involvement in
doaj
Targeting cytotoxic lymphocyte antigen 4 (CTLA-4) in breast cancer
European Journal of Medical ResearchBreast cancer (BC) has a high mortality rate and is one of the most common malignancies in the world. Initially, BC was considered non-immunogenic, but a paradigm shift occurred with the discovery of tumor-infiltrating lymphocytes (TILs) and regulatory T
Maryam Jama +2 more
doaj +1 more source
Interdisciplinary Medicine, EarlyView.Napabucasin reduces liver metastases by reprogramming the hepatic microenvironment. It induces hepatocyte secretion of CCL21 via c‐Fos activation, recruiting lymphocytes and converting “cold” metastases into immunologically “hot” tumors. This effect is liver‐specific and independent of cancer cells.
Qiongqiong Wang +19 more
wiley +1 more source
Journal of Clinical Laboratory Analysis, EarlyView.Flow cytometric analysis in sickle cell anemia reveals preserved Treg frequency despite decreased CD25 expression and increased neutrophil activity, highlighting a complex immune imbalance. The proportions of both neutrophil and lymphocyte cells have been shown to be a reliable predictor of CD3+ T cell levels, thus emphasizing the importance of innate ...
Rukiye Ölçüoğlu +7 more
wiley +1 more source
JEADV Clinical Practice, EarlyView.ABSTRACT Background Melanomas often metastasize to the brain, leading to a significantly poor prognosis despite advances in local and systemic treatments. In clinical practice, we frequently observe varying response patterns and progression dynamics between cerebral and extra cerebral sites. Objectives This study aims to identify predictive factors for
Manuel Croix +4 more
wiley +1 more source