Results 271 to 280 of about 120,218 (287)
Some of the next articles are maybe not open access.
Two CTLA-4 ligands, separate pHates
Nature Immunology, 2022Preston A. Humphries, Wan-Lin Lo
openaire +2 more sources
IFNγ Mutations Prompt CTLA-4 Inhibitor Resistance
Cancer Discovery, 2017Abstract A recent study pinpoints loss of IFNγ signaling as one reason why many patients do not respond to the CTLA-4 inhibitor ipilimumab. Analyzing whole-exome tumor sequencing data from 16 patients with melanoma, the researchers found multiple copy-number alterations that led to the loss of key IFNγ pathway genes in 12 ipilimumab ...
openaire +2 more sources