Results 91 to 100 of about 3,070 (212)

Factors Associated With Symptom Profiles Among Chinese Patients With Multiple Myeloma: A Latent Profile Analysis

open access: yesCancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Background This cross‐sectional study aimed to identify symptom profiles and their associated factors in Chinese patients with multiple myeloma, thereby providing an evidence‐based foundation for developing targeted symptom management strategies. Methods Patients with multiple myeloma were recruited via convenience sampling from the hematology
Ting Wang   +7 more
wiley   +1 more source

Effect of ELX-02 on exogenous CTNS protein expressed from pCMV-driven constructs.

open access: yes, 2019
HEK293 cells transfected with expression plasmids containing a pCMV-driven CTNS-DsRed or CTNSW138X-DsRed fusion construct. A. (Top) Confocal images show CTNS-DsRed and W138X-DsRed fluorescence without ELX-02 treatment (400 X, scale bar = 100 μm); (middle)
Pedro Huertas (4891903)   +9 more
core   +1 more source

Cancer and Hypertension: Shared Mechanisms, Treatment Interactions, and Clinical Management

open access: yesCancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Cancer and hypertension (HTN) frequently coexist, and their relationship is increasingly recognized as a clinically relevant intersection between oncology and cardiovascular medicine. However, the extent to which this association reflects shared risk factors, common biological mechanisms, or treatment‐related effects remains incompletely ...
Peizhi Jia   +5 more
wiley   +1 more source

Quantitative in vivo and ex vivo confocal microscopy analysis of corneal cystine crystals in the Ctns−/− knockout mouse [PDF]

open access: yes, 2011
PurposeThe purpose of this study was to assess the ability of quantitative in vivo confocal microscopy to characterize the natural history and detect changes in crystal volume in corneas from a novel animal model of cystinosis, the cystinosin (Ctns ...
Nien, Chyong Jy   +5 more
core   +1 more source

Characterization of mesenchymal stem cells and CTNS(−/−) mutant target cells.

open access: yes, 2013
(a) FACS analysis (left) of bmMSC surface markers (blue) and isotype controls (red) and bmMSC differentiation from baseline (upper right) to Alizarin Red S-stained calcium-containing osteogenic (middle right) and Oil-Red O-stained adipocyte (bottom right)
Reyhan El-Kares (311952)   +13 more
core   +1 more source

A serum proteomics‐based predictive model for steroid‐resistant immune checkpoint inhibitor associated myocarditis

open access: yesClinical and Translational Medicine, Volume 16, Issue 10, October 2026.
The research methods and clinical applications of this predictive score. (1) A pretreatment serum protein‐based score was established and externally validated to predict srICIAM. (2) The post‐treatment trajectory of IL‐22RA1 differed between patients with ssICIAM and srICIAM.
Yerui Zhang   +11 more
wiley   +1 more source

Effect of ELX-02 on cystine accumulation and CTNS transcription in embryonic fibroblasts derived from the CtnsY226X/Y226X mice.

open access: yes, 2019
A. Half-cystine in MEFs from CtnsY226X/Y226X mice was progressively decreased by ELX-02 (0, 100, 200 and 400 μg/mL). B. Ctns transcript levels (RT-qPCR) in CtnsY226X/Y226X MEFs were increased by ELX-02 (200 μg/mL).
Pedro Huertas (4891903)   +9 more
core   +1 more source

Glycoproteomic Signatures of IgG Subclass N‐Glycosylation Reveal Molecular Endotypes in Idiopathic Inflammatory Myopathies

open access: yesMedComm, Volume 7, Issue 10, October 2026.
• EThcD‐sceHCD‐MS/MS and updated PANDA software decode IgG N‐glycosylation in IIMs. • Unsupervised clustering reveals three novel glyco‐endotypes matching clinical phenotypes. • A seven‐glycopeptide model enables robust endotype prediction beyond conventional subtypes.
Tong Wu   +9 more
wiley   +1 more source

Cadenas globales de suministro y activos intangibles en las industrias del automóvil y aeronáutica [PDF]

open access: yesOla Financiera, 2019
La relocalización de las corporaciones transnacionales (CTNs) de las actividades de alta generación de valor ya sea en el más alto nivel (diseño, desarrollo, marcas y propiedad intelectual) o en el más bajo (comercialización, mantenimiento y servicios ...
Claude Serfati , Catherine Sauviat
doaj  

Collaborative care intervention for risky opioid use among primary care patients: The STOP randomized clinical trial

open access: yesAddiction, Volume 121, Issue 10, Page 2807-2821, October 2026.
Abstract Background and aims Individuals who engage in illicit or nonmedical opioid use may have elevated risk of health and social consequences, including progression to opioid use disorder (OUD). Preventive interventions to reduce this risk are lacking. This trial tested the impact of a primary care‐integrated collaborative care approach for reducing
Jennifer McNeely   +23 more
wiley   +1 more source

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