Results 81 to 90 of about 3,070 (212)

An unusual titanosaur axis from the Upper Cretaceous of Brazil and its significance for sauropod anatomy and systematics

open access: yesThe Anatomical Record, Volume 309, Issue 11, Page 3137-3168, November 2026.
Abstract The Upper Cretaceous São José do Rio Preto Formation (Bauru Group, southeastern Brazil) has yielded a fragmentary but taxonomically diverse record of titanosaur sauropods, although elements from cervical series remain scarce. Here, we describe a nearly complete sauropod axis from the Vila Ventura Paleontological Area, representing an uncommon ...
Bruno A. Navarro   +7 more
wiley   +1 more source

Genetic organisation, mobility and predicted functions of genes on integrated, mobile genetic elements in sequenced strains of Clostridium difficile.

open access: yesPLoS ONE, 2011
BackgroundClostridium difficile is the leading cause of hospital-associated diarrhoea in the US and Europe. Recently the incidence of C. difficile-associated disease has risen dramatically and concomitantly with the emergence of 'hypervirulent' strains ...
Michael S M Brouwer   +4 more
doaj   +1 more source

Essential Oral Single Nutritional Therapy Products for Inherited Metabolic Diseases: Evidence and Consensus Assessment Using a Modified Delphi Method

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Nutritional therapy is critical in managing inherited metabolic diseases (IMDs), and includes specialized diets and single nutritional therapy products (sNTPs) such as vitamins, cofactors, and amino acids. Many sNTPs function as medicines, but are regulated as food (e.g., food supplements), which can limit access, reimbursement, and consistent
Nina N. Stolwijk   +39 more
wiley   +1 more source

Evaluation of topical cysteamine therapy in the CTNS−/− knockout mouse using in vivo confocal microscopy [PDF]

open access: yes, 2011
PurposeThe purpose of this study was to assess the ability of quantitative in vivo confocal microscopy (CM) to detect changes in cystine crystal volume in the cystinosisn (Ctns−/−)mouse cornea following topical cysteamine therapy.MethodsFifteen Ctns ...
Nien, Chyong Jy   +3 more
core   +1 more source

Compositional Time–Temperature–Transformation and Post‐Processing Window Mapping of Epoxy Nanocomposites via Machine Learning

open access: yesJournal of Applied Polymer Science, Volume 143, Issue 40, October 20, 2026.
Discrete DSC and rheological data are transformed into continuous compositional Time–temperature–transformation (TTT) diagrams through physics‐informed Gaussian Process Regression. The proposed framework quantitatively predicts post‐gel processing windows across temperature and nanofiller composition, providing a practical route for accelerated design ...
Otávio Bianchi   +6 more
wiley   +1 more source

Hypertension, but Not Cancer or Obesity, Is Compatible With Extreme Longevity: A Multi‐Institution Analysis of 733,919 US Centenarians

open access: yes
Journal of the American Geriatrics Society, EarlyView.
Fateme Nateghi Haredasht   +5 more
wiley   +1 more source

Characterization of animal tissues for Monte Carlo simulations in ion beam therapy

open access: yesJournal of Applied Clinical Medical Physics, Volume 27, Issue 10, October 2026.
Abstract Purpose To obtain better elemental compositions (ECs), physical densities (PDs), and relative linear stopping powers (RLSPs) of tissues scanned by single or dual energy computed tomography for use by Monte Carlo (MC) simulations of light ion beam therapy.
Liu Xiaoli, Michael F. Moyers
wiley   +1 more source

Clinical, biochemical, and molecular spectrum of nephropathic cystinosis: Two novel CTNS mutations

open access: yesSaudi Journal of Kidney Diseases and Transplantation
Background: Nephropathic cystinosis (NC) is an autosomal recessive disease. Mutations in the CTNS gene encoding the lysosomal membrane cystine transporter cystinosin are identified as the molecular basis of cystinosis.
Zeinab Youssef Abdallah   +10 more
doaj   +1 more source

Infection Profiles Under Venetoclax‐Based Therapy in Newly Diagnosed Acute Myeloid Leukemia: A Real‐World Study

open access: yesCancer Medicine, Volume 15, Issue 10, October 2026.
Study on infection profiles under venetoclax‐based therapy in ND‐AML. ABSTRACT Venetoclax (VEN)‐based regimens improve remission in acute myeloid leukemia (AML), but infectious toxicity remains a concern. We compared infection profiles under VEN‐based versus conventional therapy in newly diagnosed, non‐M3 AML at a single tertiary center (2015–2024; n = 
Guilin Ren   +10 more
wiley   +1 more source

Disruption of a cystine transporter downregulates expression of genes involved in sulfur regulation and cellular respiration

open access: yesBiology Open, 2016
Cystine and cysteine are important molecules for pathways such as redox signaling and regulation, and thus identifying cellular deficits upon deletion of the Saccharomyces cerevisiae cystine transporter Ers1p allows for a further understanding of cystine
Jessica A. Simpkins   +10 more
doaj   +1 more source

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