Results 61 to 70 of about 57,597 (259)

Global dissemination of a multidrug resistant Escherichia coli clone. [PDF]

, 2014
Escherichia coli sequence type 131 (ST131) is a globally disseminated, multidrug resistant (MDR) clone responsible for a high proportion of urinary tract and bloodstream infections. The rapid emergence and successful spread of E.
A. Pascual, Alikhan, B. A. Rogers, B. M. Forde, Bruant, Canton, Castresana, Coque, Croucher, D. Gomes Moriel, D. L. Paterson, Darling, Didelot, E. Skippington, G. Dougan, Harris, Holt, J. D. D. Pitout, J. Rodriguez-Bano, Johnson, K. M. Peters, Lavigne, M. A. Schembri, M. Davies, M. Stanton-Cook, M. Totsika, M. Upton, M.-D. Phan, Martincorena, N. K. Petty, N. L. Ben Zakour, Ren, S. A. Beatson, Selkrig, T. R. Walsh, Totsika, Touchon, Uchida, Whitfield   +38 more
core   +3 more sources

Prolonged febrile illness due to CTX-M-15 extendedspectrum β-lactamase-producing Klebsiella pneumoniae infection in Nigeria

African Journal of Laboratory Medicine, 2012
We report on an 8-year-old patient with septicaemia unresponsive to therapy for five weeks. Undetected, extended-spectrum β-lactamase (ESBL) production by the infecting Klebsiella strain was regarded as responsible for treatment failure.
Oladipo A. Aboderin, Olufemi Adefehinti, Babatunde W. Odetoyin, Amadin A. Olotu, Iruka N. Okeke, Olugbenga Adeodu   +5 more
doaj   +1 more source

Novel chromosomal insertions of ISEcp1-bla CTX-M-15 and diverse antimicrobial resistance genes in Zambian clinical isolates of Enterobacter cloacae and Escherichia coli

Antimicrobial Resistance and Infection Control, 2021
Background The epidemiology of extended-spectrum β-lactamases (ESBLs) has undergone dramatic changes, with CTX-M-type enzymes prevailing over other types. bla CTX-M genes, encoding CTX-M-type ESBLs, are usually found on plasmids, but chromosomal location
Misheck Shawa, Yoshikazu Furuta, Gillan Mulenga, Maron Mubanga, Evans Mulenga, Tuvshinzaya Zorigt, Christone Kaile, Manyando Simbotwe, Atmika Paudel, Bernard Hang’ombe, Hideaki Higashi   +10 more
doaj   +1 more source

Cephem Potentiation by Inactivation of Nonessential Genes Involved in Cell Wall Biogenesis of ß-Lactamase-Producing Escherichia coli [PDF]

, 2017
Reversal of antimicrobial resistance is an appealing and largely unexplored strategy in drug discovery. The objective of this study was to identify potential targets for “helper” drugs reversing cephem resistance in Escherichia coli strains producing β ...
Baker, K R, Guardabassi, L, Jana, B, Sigurðardóttir, H H   +3 more
core   +2 more sources

Molecular characteristics of extended-spectrum β-lactamases in clinical isolates from Escherichia coli at a Japanese tertiary hospital.

PLoS ONE, 2013
The prevalence of ESBL has been increasing worldwide. In this study, we investigated the molecular characteristics of ESBL among clinical isolates of Escherichia coli from a Japanese tertiary hospital.
Hisakazu Yano, Mina Uemura, Shiro Endo, Hajime Kanamori, Shinya Inomata, Risako Kakuta, Sadahiro Ichimura, Miho Ogawa, Masahiro Shimojima, Noriomi Ishibashi, Tetsuji Aoyagi, Masumitsu Hatta, Yoshiaki Gu, Mitsuhiro Yamada, Koichi Tokuda, Hiroyuki Kunishima, Miho Kitagawa, Yoichi Hirakata, Mitsuo Kaku   +18 more
doaj   +1 more source

Primer relevamiento de marcadores de resistencia a antibióticos en Enterobacteriaceae en Cochabamba, Bolivia [PDF]

, 2017
Se llevó a cabo un relevamiento molecular de la resistencia a antibióticos de importancia clínica en aislamientos recuperados en Cochabamba, Bolivia. Se estudiaron los genes codificantes de β-lactamasas de espectro extendido y de resistencia a quinolonas
Di Conza, José Alejandro, Gutkind, Gabriel Osvaldo, Radice, Marcela Alejandra, Saba Villarroel, Paola M.   +3 more
core   +1 more source

Detection of O25b-ST131 clone, CTX-M-1 and CTX-M-15 genes via real-time PCR in Escherichia coli strains in patients with UTIs obtained from a university hospital in Istanbul

Journal of Infection and Public Health, 2019
Background: Escherichia coli sequence type 131 is an important multidrug resistant clone responsible from more than half of ESBL-producing E.coli isolates.
Mehmet Demirci, Özge Ünlü, Ayşe İstanbullu Tosun   +2 more
doaj   +1 more source

Whole Genome Characterization of the High-Risk Clone ST383 Klebsiella pneumoniae with a Simultaneous Carriage of bla_CTX-M-14 on IncL/M Plasmid and bla_CTX-M-15 on Convergent IncHI1B/IncFIB Plasmid from Egypt

Microorganisms, 2022
Recently, Egypt has witnessed the emergence of multidrug-resistant (MDR) Klebsiella pneumoniae, which has posed a serious healthcare challenge. The accelerated dissemination of blaCTX-M genes among these MDR K.
Eva A. Edward, Nelly M. Mohamed, Azza S. Zakaria   +2 more
doaj   +1 more source

Emergence of CTX-M-15-Producing Enterobacteria in Cameroon and Characterization of a bla _CTX-M-15 -Carrying Element [PDF]

Antimicrobial Agents and Chemotherapy, 2005
ABSTRACT CTX-M-15-producing Klebsiella pneumoniae and Escherichia coli emerged recently in Cameroon. CTX-M-15 was encoded by two different multiresistance plasmids, of which one carried an IS Ecp1 - bla CTX-M-15 element ...
Gangoue-Pieboji, J., Miriagou, V., Vourli, S., Tzelepi, E., Ngassam, P., Tzouvelekis, L.S.   +5 more
openaire   +3 more sources

Characterization of CTX-M-14 and CTX-M-15 producing Escherichia coli strains causing neonatal sepsis [PDF]

, 2017
Neonatal sepsis is a disease affecting newborns ≤1 month of age with clinical symptoms and positive blood cultures. The number of Escherichia coli strains causing neonatal sepsis resistant to the antibiotics used in the treatment is increasing.
Bosch Mestres, Jordi, Guiral Vilalta, Elisabet, López, Yuly, Montero, Ignacio, Soto González, Sara M., Sáez-López, Emma, Vila Estapé, Jordi   +6 more
core   +1 more source