Results 191 to 200 of about 15,378 (241)

Affinity-based protein profiling of the antiviral natural product nanchangmycin. [PDF]

open access: yesRSC Chem Biol
Leiva S   +4 more
europepmc   +1 more source

Engineering protein prenylation: an emerging tool for selective protein modification. [PDF]

open access: yesBiochem Soc Trans
Venkatachalapathy S   +3 more
europepmc   +1 more source
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Copper-Mediated Intramolecular Interrupted CuAAC Selanylation

The Journal of Organic Chemistry, 2023
We, herein, describe a copper-mediated domino CuAAC intramolecular selanylation for the synthesis of unprecedented fused benzo[4,5][1,3]selenazolo[3,2-c][1,2,3]triazoles from 1,2-bis(2-azidoaryl)diselenides and terminal alkynes under microwave irradiation.
Wystan K. O. Teixeira   +5 more
openaire   +2 more sources

Biocompatible photoinduced CuAAC using sodium pyruvate

Chemical Communications, 2021
The use of sodium pyruvate as a photoreducing agent for copper-mediated azide–alkyne cycloaddition (CuAAC) under UV irradiation is described.
Jaepil Jeong   +7 more
openaire   +3 more sources

Polymer “Clicking” by CuAAC Reactions

Macromolecular Rapid Communications, 2008
AbstractThe CuAAC “click” reaction has developed as one of the most useful and widely employed reactions in ligation within polymer chemistry. This is due to the unique properties of the Cu(I) catalysis which renders the reaction quantitative even at low concentrations, orthogonal with other chemistries and extremely robust.
Morten Meldal
exaly   +2 more sources

2.1 Introduction to CuAAC

2022
AbstractThe basic principles of the copper-catalyzed azide–alkyne cycloaddition reaction (CuAAC), widely considered to be the first click reaction, are described. This involves amongst others the concept of click reactions, the mechanism of CuAAC, the synthesis and reactivity of organic azides and acetylenes, an overview of most commonly used copper(I)
F. F. Ort, F. P. J. T. Rutjes
openaire   +1 more source

A Fluxional Copper Acetylide Cluster in CuAAC Catalysis

Angewandte Chemie - International Edition, 2015
AbstractA molecularly defined copper acetylide cluster with ancillary N‐heterocyclic carbene (NHC) ligands was prepared under acidic reaction conditions. This cluster is the first molecular copper acetylide complex that features high activity in copper‐catalyzed azide–alkyne cycloadditions (CuAAC) with added acetic acid even at −5 °C.
Ata Makarem   +2 more
exaly   +3 more sources

2.4 CuAAC in Carbohydrate Conjugation

2022
AbstractCopper(I)-catalyzed azide–alkyne cycloaddition reactions (CuAAC), as a versatile, reliable, and modular strategy, have been widely investigated in the area of glycoscience during the last 20 years. Herein, we presented a brief overview of CuAAC click approaches for easy access to diverse simple and complex triazole-appended carbohydrate ...
A. K. Agrahari, A. Mishra, V. K. Tiwari
openaire   +1 more source

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