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‘Click’ glycosylation of peptides through cysteine propargylation and CuAAC

open access: yesBioorganic and Medicinal Chemistry, 2014
'Click' glycosylation of cysteine-containing peptides were carried out in good yield by Copper(I)-catalyzed Azide-Alkyne Cycloaddition (CuAAC). For that peptides were functionalized though direct propargylation of the cysteine residue allowing their use in CuAAC with suitable free or protected azido sugars of gluco, manno and galacto configuration ...
Véronique Régnault   +2 more
exaly   +5 more sources

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