Results 151 to 160 of about 6,459 (197)

Development of Glycoconjugated MAGL Inhibitors with Glucose-Dependent Antiproliferative Activity. [PDF]

open access: yesInt J Mol Sci
Bononi G   +10 more
europepmc   +1 more source

Click Chemistry Functionalization of Harmonic Nanoparticles with Lanthanide Complexes Towards Tunable Platforms for Multimodal Imaging. [PDF]

open access: yesNanomaterials (Basel)
Dumolard S   +11 more
europepmc   +1 more source

Iterative Bump-and-hole engineering creates a bioorthogonal reporter for N -acetylglucosaminyltransferase I

open access: yes
Liu Y   +13 more
europepmc   +1 more source
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Polymer “Clicking” by CuAAC Reactions

Macromolecular Rapid Communications, 2008
AbstractThe CuAAC “click” reaction has developed as one of the most useful and widely employed reactions in ligation within polymer chemistry. This is due to the unique properties of the Cu(I) catalysis which renders the reaction quantitative even at low concentrations, orthogonal with other chemistries and extremely robust.
Morten Meldal
exaly   +2 more sources

A Fluxional Copper Acetylide Cluster in CuAAC Catalysis

Angewandte Chemie - International Edition, 2015
AbstractA molecularly defined copper acetylide cluster with ancillary N‐heterocyclic carbene (NHC) ligands was prepared under acidic reaction conditions. This cluster is the first molecular copper acetylide complex that features high activity in copper‐catalyzed azide–alkyne cycloadditions (CuAAC) with added acetic acid even at −5 °C.
Bernd F Straub   +2 more
exaly   +3 more sources

Recent Fascinating Aspects of the CuAAC Click Reaction

Trends in Chemistry, 2020
CuAAC chemistry is used to compose incredible synthetic molecular architectures and acts as a true click chemistry reaction allowing densely functional molecular fragments to be joined in a highly controlled manner. Using supercatalysts based on our mechanistic understanding and in the absence of oxygen, CuAAC reactions are superior even in bioligation
Frederik Diness, Morten Meldal
exaly   +3 more sources

4-Azidotetrahydroquinazoline derivatives in CuAAC reaction

Mendeleev Communications, 2020
4-Azido-2-methyltetrahydroquinazoline N-oxide cleanly undergoes the copper( i )-catalyzed azide–alkyne cycloaddition (CuAAC) reaction with alkynes to give new conjugates with pyrimidine N-oxide and triazole moieties. Its deoxygenated analogue, 4-azido-2-methyltetrahydroquinazoline, is inert in CuACC process due to the shift of imidoyl azide–tetrazole ...
Yuri Grishin   +2 more
exaly   +2 more sources

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