Results 131 to 140 of about 15,378 (241)
ChemSusChem, Volume 19, Issue 9, 14 May 2026.A telescoped three‐step continuous flow process enables the synthesis of organophosphorus 1,2,3‐triazoles in the biomass‐derived solvent γ‐valerolactone (GVL). The sequence integrates N‐phosphorylation, azidation, and Cu(I)‐catalyzed azide–alkyne cycloaddition (CuAAC), followed by in‐line copper removal, giving diverse triazoles in good to high overall
Viktória Gerő +3 more
wiley +1 more source
Angewandte Chemie, Volume 138, Issue 17, 20 April 2026.The cupula is a membrane within the vestibular organ that senses rotatory accelerations of the head. Metabolic glycoengineering in combination with bioorthogonal labeling demonstrates that in adult zebrafish – being a model for the human inner ear – this membrane is constantly renewed.
Hans Scherer +4 more
wiley +2 more sources
Angewandte Chemie, Volume 138, Issue 17, 20 April 2026.This minireview highlights recent advances in catalyst development and mechanistic strategies that enable photochemical and photocatalytic reactivity under 700–1000 nm NIR light, emphasizing how long‐wavelength excitation expands opportunities in both synthetic chemistry and biology.
Santosh K. Pagire +3 more
wiley +2 more sources
ChemistryEurope, Volume 4, Issue 5, May 2026.Mannose derivatives connected to the aminophilic salicylaldehyde tag show high binding affinity for C‐type lectin DC‐SIGN, favored by an imine bond with a protein's Lys residue in the ligand binding site. This reversible‐covalent binding interaction enables ligand selectivity for DC‐SIGN over the closely related L‐SIGN.
Sara Pollastri +11 more
wiley +1 more source
ReactionsDespite multiple advances in treatment and prevention, cancer remains one of the leading causes of death worldwide. Chemotherapy remains the most effective method for cancer treatment.
Delia Hernández-Romero +7 more
doaj +1 more source
ChemistryEurope, Volume 4, Issue 5, May 2026.Polyoxometalates (POMs), illustrated as lemon‐like cars racing along a winding road, symbolize the accelerating progress of POM research toward technological applications. Global research communities, recent advances, and emerging opportunities highlight how coordinated efforts drive the transition of POM science from molecular discovery to deployable ...
Kirill Monakhov +15 more
wiley +1 more source
Zwitterionic Mn(III)‐Tetraphenyl Porphyrins: Water‐Soluble MRI Contrast Agents with High Relaxivity
ChemMedChem, Volume 21, Issue 8, 28 April 2026.Mn(III)‐based contrast agents (MBCAs) are promising and potentially safer alternatives to the Gd(III)‐based contrast agents (GBCAs) currently used in MRI. This study reports the synthesis, physicochemical characterization and first in vivo application of novel Mn(III)‐tetraphenylporphyrin chelates, bearing zwitterionic sulfobetaine or N‐oxide groups ...
Darius Ludolfs +10 more
wiley +1 more source
Chemistry – A European Journal, Volume 32, Issue 15, 22 April 2026.We report an efficient method for late‐stage installation of “clickable” alkyne groups into diverse (hetero)arenes. Using a dual‐ligand palladium catalyst that combines an NASA ligand with an N‐heterocycle, an acrylate unit bearing a terminal alkyne can be introduced via nondirected C─H activation.
Tommaso Braga +2 more
wiley +1 more source
A Bifunctional Small Molecule Degrader of the Long Noncoding RNA MALAT1 Triplex
Chemistry – A European Journal, Volume 32, Issue 15, 22 April 2026.Targeting disease‐linked RNAs with small molecules is often limited by the modest impact of binding RNA structure alone. Here, we present a first‐in‐class bifunctional molecule that degrades the oncogenic lncRNA MALAT‐1 by inducing proximity between the RNA and a cleaving warhead.
Christian A. T. Brega +12 more
wiley +1 more source
MoleculesRadiolabeled peptides are valuable tools for diagnosis or therapies; they are often radiofluorinated using an indirect approach based on an F-18 prosthetic group.
Timothé Maujean +8 more
doaj +1 more source