Results 121 to 130 of about 15,378 (241)
Chemoselective sequential click ligations directed by enhanced reactivity of an aromatic ynamine [PDF]
, 2016 Aromatic ynamines or N-alkynylheteroarenes are highly reactive alkyne components in Cu-catalyzed Huisgen [3 +2] cycloaddition (“click”) reactions. This enhanced reactivity enables the chemoselective formation of 1,4-triazoles using the representative ...
Burley, Glenn A. +8 more
core +1 more source
Macromolecular Rapid Communications, EarlyView.Little is known about the cellular uptake of single chain nanoparticles that are cross‐linked with dynamic bonds. Using Förster resonance energy transfer and fluorescence lifetime imaging microscopy (FRET‐FLIM) the dynamic nature of the bonds is seen, in which the interaction between two peptides, disassemble quickly, relatively.
Shegufta Farazi +5 more
wiley +1 more source
Synthesis of [(1,2,3-Triazol-1-yl)methyl]boronic Acids Through Click Chemistry: Easy Access to a Potential Scaffold for Protease Inhibitors [PDF]
, 2015 Stereoselective synthesis of previously unreported [(1,2,3-triazol-1-yl)methyl]boronic acids has been achieved from azidomethylboronates by copper-catalyzed azide–alkyne cycloaddition reaction.
CASELLI, Emilia +2 more
core +1 more source
Macromolecular Rapid Communications, EarlyView.Diacetylene‐containing glycan mimetics cluster upon selective lectin binding in GUVs. Subsequent irradiation leads to the formation of fluorescent polymer clusters, while non‐clustered glycan mimetics remain unaffected in the membrane. ABSTRACT The glycocalyx, a dense layer of glycoproteins and glycolipids on eukaryotic cells, is essential for cellular
Luca‐Cesare Blawitzki +5 more
wiley +1 more source
Synthesis of EDTA core dendrimers through a consecutive esterification-CuAAC process [PDF]
, 2017 Artículo para obtención de grado de DoctorA novel class of thermostable G0 and G1-dendrimers was synthesized from the coupling of both propargyl and azido esters derived from EDTA through copper catalyzed azide-alkyne cycloaddition.
Apolonio, Víctor M. +5 more
core +1 more source
A Non‐Antigenic Randomized Polyethylene Glycol/Poly(2‐Phenyl‐2‐Oxazine)‐Based Drug Delivery Platform
Macromolecular Rapid Communications, EarlyView.Randomized PEG (rPEG), a conceptually new PEG alternative, is combined with poly(2‐phenyl‐2‐oxazine) (PPheOzi) to establish an rPEG‐b‐PPheOzi‐b‐rPEG micellar drug delivery platform. The PPheOzi block enables high drug loadings, while competitive ELISA reveals a drastic reduction in anti‐PEG antibody affinity of rPEG in comparison to PEG.
Julian Schmidt +6 more
wiley +1 more source
Safirinium Fluorescent “Click” Molecular Probes: Synthesis, CuAAC Reactions, and Microscopic Imaging
MoleculesFluorescent labeling utilizing Cu(I)-catalyzed azide–alkyne cycloaddition reactions (CuAAC) is among the leading applications of the “click” chemistry strategy.
Patryk Kasza +10 more
doaj +1 more source
Molecules, 2016 The explosively-growing applications of the Cu-catalyzed Huisgen 1,3-dipolar cycloaddition reaction between organic azides and alkynes (CuAAC) have stimulated an impressive number of reports, in the last years, focusing on recoverable variants of the ...
Alessandro Mandoli
doaj +1 more source
The Chemical Record, EarlyView.This review highlights recent advances in the use of organic carbonates, dimethyl carbonate (DMC), diethyl carbonate (DEC), and propylene carbonate (PC), as solvents in organic synthesis. Based on over seventy studies from the past 6 years, it shows their application in different organic reaction types, emphasizing their role in safer and more ...
Gabriela T. Quadros +5 more
wiley +1 more source
Beilstein Journal of Organic Chemistry, 2015 3-Azido-1-propyne oligomer (oligoAP) samples, prepared by copper(I)-catalyzed azide–alkyne cycloaddition (CuAAC) polymerization, were quarternized quantitatively with methyl iodide in sulfolane at 60 °C to obtain soluble oligomers.
Shun Nakano +2 more
doaj +1 more source