Results 101 to 110 of about 15,378 (241)
Unnatural Amino Acid Incorporation into Virus-Like Particles [PDF]
, 2008 Virus-like particles composed of hepatitis B virus (HBV) or bacteriophage Qβ capsid proteins have been labeled with azide- or alkyne-containing unnatural amino acids by expression in a methionine auxotrophic strain of E. coli.
Brown, Steven +11 more
core +2 more sources
Self‐Immolative Gels: Programmable Degradation Using Self‐Immolative Linkers and Polymers
Chemistry – A European Journal, EarlyView.Self‐immolative linkers and polymers undergo bond‐cleaving reaction cascades in response to specific stimuli. Their incorporation into gels can be harnessed to release cargo, induce property changes, or trigger degradation in a highly controlled manner. These functions can be employed in applications such as sensing and drug delivery.
Chuanfeng Li, Elizabeth R. Gillies
wiley +1 more source
Click Chemistry (CuAAC) and Detection of Tagged de novo Synthesized Proteins in Drosophila
Bio-Protocol, 2019 Copper-catalyzed azide-alkyne-cycloaddition (CuAAC), also known as ‘click chemistry’ serves as a technique for bio-orthogonal, that is, bio-compatible labeling of macromolecules including proteins or lipids.
Kathrin Marter +8 more
doaj +1 more source
Optically pure heterobimetallic helicates from self-assembly and click strategies [PDF]
Single diastereomer, diamagnetic, octahedral Fe(II) tris chelate complexes are synthesised that contain three pendant pyridine proligands pre-organised for coordination to a second metal.
Clarkson, Guy J. +5 more
core +1 more source
Chemical Architecture and Applications of Nucleic Acid Derivatives Containing 1,2,3-Triazole Functionalities Synthesized via Click Chemistry [PDF]
, 2012 There is considerable attention directed at chemically modifying nucleic acids with robust functional groups in order to alter their properties. Since the breakthrough of copper-assisted azide-alkyne cycloadditions (CuAAC), there have been several ...
Addepalli +40 more
core +1 more source
Chemistry – A European Journal, EarlyView.This review highlights biocatalytic prenylation as a versatile strategy for tailoring the functional properties of peptides and proteins. By comparing branched isoprenoids with linear lipids, we illustrate how specific prenyl architectures modulate the behaviors of lipidated proteins within membrane environments.
Daisuke Fujinami +2 more
wiley +1 more source
Revisiting the mechanism of the mono nuclear copper-catalyzed cycloaddition of azide and alkynes (CuAAC) by the topology of .... [PDF]
, 2013 Comunicación presentada y aceptada en el CHITEL2013, XXXIX International Conference THEORETICAL CHEMISTS OF LATIN EXPRESSION (XXXIX Congreso Internacional de Químicos de Expresión Latina).Se analiza el mecanismo de la reacción de cicloadición, catalizada
Calvo-Losada, Saturnino +2 more
core
Click Chemistry in Materials Science [PDF]
, 2014 Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/106803/1/adfm201302847 ...
Bowman, Christopher N. +3 more
core +1 more source
Chemistry – A European Journal, EarlyView.This work introduces the concept of pseudoglucosinolates (psGSLs) and reports the synthesis and evaluation of nitroreductase‐responsive psGSLs. These compounds represent a complementary prodrug strategy to natural glucosinolates (GSLs) for the controlled release of isothiocyanates (ITCs), enabling bio‐responsive protein labeling, as demonstrated in ...
Claire C. Jimidar +13 more
wiley +1 more source
Synthesis, Functionalization, and Reactivity of Vinyl Sulfondiimidamides
Angewandte Chemie, Volume 138, Issue 19, 4 May 2026.Combining unsymmetrical sulfurdiimide reagents (R‐NSN‐R1) and Grignard reagents, followed by oxidative amination, delivers a series of vinyl sulfondiimidamides. Reactivity with cysteine and lysine derivatives is shown, and the cysteine reactivity is mapped in detail. Variation of the two imidic N‐substituents can be used to tune reactivity of these new
Katherine G. Rodden +4 more
wiley +2 more sources